Protein Ontology Report - hAURKB PR:Q96GD4 - http://purl.obolibrary.org/obo/PR_Q96GD4

This page represents a class of proteins encompassing all the protein products of the AURKB gene in human .

Ontology Information
PRO ID	PR:Q96GD4 Show OBO stanza / PAF
PRO name	aurora kinase B (human)
Synonyms	PRO-short-label: hAURKB BROAD: STK-1 (human) EXACT: AIM-1 (human); ARK-2 (human); aurora 1 (human); aurora- and IPL1-like midbody-associated protein 1 (human); aurora-related kinase 2 (human); aurora/IPL1-related kinase 2 (human); serine/threonine-protein kinase 12 (human); serine/threonine-protein kinase 5 (human); serine/threonine-protein kinase aurora-B (human) Gene-based: AIK2; AIM1; AIRK2; ARK2; AURKB; STK1; STK12; STK5
Definition	An aurora kinase B that is encoded in the genome of human. [PMID:12719470, PMID:15592459, PMID:15917996, PMID:17617734, PMID:20624902, PMID:21658950, PMID:22732840, PRO:KER]
PRO Category	organism-gene
Parent	PR:000004517 aurora kinase B
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 5 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100036, HGNC:11390, Reactome:R-HSA-174231, Reactome:R-HSA-4655360, UniProtKB:Q96GD4

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035661 hAURKB/PhosRes- capable_of GO:0005515 protein binding with PR:Q9NQS7 hINCENP PMID:22024163 located_in GO:0000776 kinetochore PMID:22024163 PR:Q96GD4 hAURKB capable_of GO:0005515 protein binding with PR:Q12834 hCDC20 BioGRID:BG-684898 capable_of GO:0005515 protein binding with PR:O15392 hBIRC5 BioGRID:BG-571501, IntAct:EBI-979359, MINT:MINT-4509558 capable_of GO:0005515 protein binding with PR:P06493 hCDK1 IntAct:EBI-1397755 capable_of GO:0005515 protein binding with PR:Q9NQS7 hINCENP BioGRID:BG-251075, IntAct:EBI-1555366, MINT:MINT-77928 capable_of GO:0005515 protein binding with PR:Q13043 hSTK4 PMID:20171103 capable_of GO:0005515 protein binding with PR:Q53HL2 hCDCA8 BioGRID:BG-251030 capable_of GO:0005515 protein binding with PR:O60566 hBUB1B BioGRID:BG-717913 capable_of GO:0005515 protein binding with PR:P68431 hH3.1 BioGRID:BG-530650 capable_of GO:0004672 protein kinase activity PMID:12719470 capable_of GO:0005515 protein binding with PR:Q71DI3 hH3.2 BioGRID:BG-725715 capable_of GO:0005515 protein binding with PR:Q15208 hSTK38 PMID:20171103 located_in GO:0000779 condensed chromosome, centromeric region PMID:12719470, PMID:15917996 located_in GO:0051233 spindle midzone PMID:15917996 located_in GO:0030496 midbody PMID:15917996 located_in GO:0000939 inner kinetochore PMID:15592459 located_in GO:0000776 kinetochore PMID:20624902 participates_in GO:0008608 attachment of spindle microtubules to kinetochore PMID:12719470, PMID:15592459 participates_in GO:0051310 metaphase plate congression PMID:12719470, PMID:22732840 participates_in GO:0140014 mitotic nuclear division PMID:12719470 participates_in NOT GO:0051306 mitotic sister chromatid separation PMID:12719470 participates_in GO:0007059 chromosome segregation PMID:12719470 participates_in GO:0034501 protein localization to kinetochore PMID:12719470, PMID:17617734, PMID:22732840 participates_in GO:0031577 spindle checkpoint signaling PMID:12719470 participates_in GO:0071459 protein localization to chromosome, centromeric region PMID:12719470, PMID:21658950 PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 capable_of GO:0005515 protein binding with PR:Q9NQS7 hINCENP PMID:22024163 capable_of GO:0004672 protein kinase activity increased relative to PR:000035661 hAURKB/PhosRes- PMID:17276342, PMID:22024163 located_in GO:0000776 kinetochore PMID:22024163 participates_in GO:0051310 metaphase plate congression increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 participates_in GO:0031577 spindle checkpoint signaling increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 participates_in GO:0007059 chromosome segregation increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 Biological Process GO Term Protein Forms & Complexes Evidence GO:0051310 metaphase plate congression PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 PR:Q96GD4 hAURKB PMID:12719470, PMID:22732840 NOT GO:0051306 mitotic sister chromatid separation PR:Q96GD4 hAURKB PMID:12719470 GO:0007059 chromosome segregation PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 PR:Q96GD4 hAURKB PMID:12719470 GO:0008608 attachment of spindle microtubules to kinetochore PR:Q96GD4 hAURKB PMID:12719470, PMID:15592459 GO:0034501 protein localization to kinetochore PR:Q96GD4 hAURKB PMID:12719470, PMID:17617734, PMID:22732840 GO:0031577 spindle checkpoint signaling PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 increased relative to PR:000035661 hAURKB/PhosRes- PMID:22024163 PR:Q96GD4 hAURKB PMID:12719470 GO:0071459 protein localization to chromosome, centromeric region PR:Q96GD4 hAURKB PMID:12719470, PMID:21658950 GO:0140014 mitotic nuclear division PR:Q96GD4 hAURKB PMID:12719470 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000779 condensed chromosome, centromeric region PR:Q96GD4 hAURKB PMID:12719470, PMID:15917996 GO:0051233 spindle midzone PR:Q96GD4 hAURKB PMID:15917996 GO:0000939 inner kinetochore PR:Q96GD4 hAURKB PMID:15592459 GO:0000776 kinetochore PR:000035661 hAURKB/PhosRes- PMID:22024163 PR:000035663 hAURKB/Phos:1 Ser-331, MOD:00046 PMID:22024163 PR:Q96GD4 hAURKB PMID:20624902 GO:0030496 midbody PR:Q96GD4 hAURKB PMID:15917996

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