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Protein Ontology Report - mTGFBR2

PR:Q62312 - http://purl.obolibrary.org/obo/PR_Q62312
This page represents a class of proteins encompassing all the protein products of the TGFBR2 gene in mouse .
Ontology Information
PRO ID PR:Q62312 Show OBO stanza / PAF
PRO name TGF-beta receptor type-2 (mouse)
Synonyms
PRO-short-label: mTGFBR2
EXACT: TGF-beta receptor type II (mouse); TGF-beta type II receptor (mouse); TGFR-2 (mouse); TbetaR-II (mouse); transforming growth factor-beta receptor type II (mouse)
Gene-based: Tgfbr2
Definition A TGF-beta receptor type-2 that is encoded in the genome of mouse. [OMA:Q62312, PRO:DNx]
PRO Category organism-gene
Parent PR:000000005 TGF-beta receptor type-2
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q62312-1
mTGFBR2/iso:RII-2
capable_of GO:0050431 transforming growth factor beta binding PMID:7957954
located_in GO:0016021 integral component of membrane PMID:7959019
PR:Q62312-2
mTGFBR2/iso:RII-1
located_in GO:0016021 integral component of membrane PMID:7957954
PR:000000005
TGFBR2
capable_of GO:0005515 protein binding PIRSF:PIRSF037393
capable_of GO:0004672 protein kinase activity PIRSF:PIRSF037393
has_part Pfam:PF00069 Protein kinase domain PIRSF:PIRSF037393
has_part Pfam:PF08917 Transforming growth factor beta receptor 2 ectodomain PIRSF:PIRSF037393
participates_in GO:0006468 protein phosphorylation PIRSF:PIRSF037393
participates_in GO:0042127 regulation of cell population proliferation PIRSF:PIRSF037393
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PIRSF:PIRSF037393
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006468 protein phosphorylation PR:000000005 TGFBR2

PIRSF:PIRSF037393
GO:0042127 regulation of cell population proliferation PR:000000005 TGFBR2

PIRSF:PIRSF037393
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000000005 TGFBR2

PIRSF:PIRSF037393
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0016021 integral component of membrane PR:Q62312-1 mTGFBR2/iso:RII-2

PMID:7959019
PR:Q62312-2 mTGFBR2/iso:RII-1

PMID:7957954

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