back to PRO homepage

Protein Ontology Report - mPITX2

PR:P97474 - http://purl.obolibrary.org/obo/PR_P97474
This page represents a class of proteins encompassing all the protein products of the PITX2 gene in mouse .
Ontology Information
PRO ID PR:P97474 Show OBO stanza / PAF
PRO name pituitary homeobox 2 (mouse)
Synonyms
PRO-short-label: mPITX2
EXACT: ALL1-responsive protein ARP1 (mouse); BRX1 homeoprotein (mouse); homeobox protein PITX2 (mouse); orthodenticle-like homeobox 2 (mouse); paired-like homeodomain transcription factor 2 (mouse); paired-like homeodomain transcription factor Munc 30 (mouse); solurshin (mouse)
Gene-based: Arp1; Brx1; Otlx2; Pitx2; Ptx2; Rgs
Definition A pituitary homeobox 2 that is encoded in the genome of mouse. [OMA:P97474, PRO:DNx]
PRO Category organism-gene
Parent PR:000000117 pituitary homeobox 2
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 6
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P97474-1
mPITX2/iso:Ptx2B
part_of GO:0005667 transcription factor complex PMID:12464179, PMID:15385555
participates_in GO:0007368 determination of left/right symmetry PMID:12397115
participates_in GO:0016055 Wnt signaling pathway PMID:12464179
PR:P97474-3
mPITX2/iso:Ptx2A
capable_of GO:0003712 transcription coregulator activity MGI:3796777, PMID:18458156
capable_of GO:0008134 transcription factor binding PMID:15385555
capable_of GO:0005515 protein binding with PR:Q9JM73 mSRF MGI:3796777, PMID:18458156
capable_of GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific MGI:3796777, PMID:18458156
capable_of GO:0003677 DNA binding MGI:3796777, PMID:18458156
located_in GO:0005634 nucleus MGI:3796777, PMID:18458156
located_in GO:0005634 nucleus PMID:11854422
participates_in NOT GO:0007368 determination of left/right symmetry PMID:10585561
participates_in GO:0043388 positive regulation of DNA binding MGI:3796777, PMID:18458156
participates_in GO:0007266 Rho protein signal transduction PMID:11854422
participates_in GO:0031532 actin cytoskeleton reorganization PMID:11854422
PR:P97474-2
mPITX2/iso:Ptx2C
participates_in GO:0009887 animal organ morphogenesis PMID:10585561
participates_in GO:2000288 positive regulation of myoblast proliferation MGI:3686567, PMID:16958127
participates_in GO:0007368 determination of left/right symmetry PMID:9708732
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:10585561
participates_in GO:0007520 myoblast fusion MGI:3686567, PMID:16958127
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007520 myoblast fusion PR:P97474-2 mPITX2/iso:Ptx2C

MGI:3686567, PMID:16958127
GO:0007179 transforming growth factor beta receptor signaling pathway PR:P97474-2 mPITX2/iso:Ptx2C

PMID:10585561
GO:0009887 animal organ morphogenesis PR:P97474-2 mPITX2/iso:Ptx2C

PMID:10585561
GO:0031532 actin cytoskeleton reorganization PR:P97474-3 mPITX2/iso:Ptx2A

PMID:11854422
GO:2000288 positive regulation of myoblast proliferation PR:P97474-2 mPITX2/iso:Ptx2C

MGI:3686567, PMID:16958127
GO:0016055 Wnt signaling pathway PR:P97474-1 mPITX2/iso:Ptx2B

PMID:12464179
NOT GO:0007368 determination of left/right symmetry PR:P97474-3 mPITX2/iso:Ptx2A

PMID:10585561
GO:0007266 Rho protein signal transduction PR:P97474-3 mPITX2/iso:Ptx2A

PMID:11854422
GO:0007368 determination of left/right symmetry PR:P97474-1 mPITX2/iso:Ptx2B

PMID:12397115
PR:P97474-2 mPITX2/iso:Ptx2C

PMID:9708732
GO:0043388 positive regulation of DNA binding PR:P97474-3 mPITX2/iso:Ptx2A

MGI:3796777, PMID:18458156
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:P97474-3 mPITX2/iso:Ptx2A

MGI:3796777, PMID:18458156
PR:P97474-3 mPITX2/iso:Ptx2A

PMID:11854422

top