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Protein Ontology Report - polyprot (DEN2N)

PR:P14340 - http://purl.obolibrary.org/obo/PR_P14340
This page represents a class of proteins encompassing all the protein products of the DenV-polyprot gene in Dengue virus 2 Thailand/NGS-C/1944 .
Ontology Information
PRO ID PR:P14340 Show OBO stanza / PAF
PRO name genome polyprotein (Dengue virus 2 Thailand/NGS-C/1944)
Synonyms
PRO-short-label: polyprot (DEN2N)
Definition A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Thailand/NGS-C/1944. [PRO:ES]
PRO Category organism-gene
Parent PR:000036816 dengue virus genome polyprotein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 0
organism-modification 9
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044758
NS1 (DEN2N)
Asn-905/Asn-982, MOD:00160 		located_in GO:0019034 viral replication complex PMID:23408612
participates_in GO:0019079 viral genome replication PMID:23408612
participates_in GO:0097281 immune complex formation PMID:23408612
PR:000044759
NS2A (DEN2N)
located_in GO:0019034 viral replication complex PMID:23408612
participates_in GO:0019076 viral release from host cell PMID:23408612
participates_in GO:0019079 viral genome replication PMID:23408612
participates_in GO:0019068 virion assembly PMID:23408612
PR:000044768
NS5 (DEN2N)
capable_of GO:0008168 methyltransferase activity PMID:21810535
capable_of GO:0070568 guanylyltransferase activity PMID:23408612
capable_of GO:0003968 RNA-directed 5'-3' RNA polymerase activity PMID:21810535
located_in GO:0019034 viral replication complex PMID:21810535
participates_in GO:0042783 evasion of host immune response PMID:21810535
participates_in GO:0019079 viral genome replication PMID:21810535
participates_in GO:0001510 RNA methylation PMID:21810535
PR:000044761
NS2B (DEN2N)
capable_of GO:0008236 serine-type peptidase activity PMID:10744671
participates_in GO:1900005 positive regulation of serine-type endopeptidase activity PMID:10744671
PR:000044763
NS4A (DEN2N)
located_in GO:0019034 viral replication complex PMID:17276984
participates_in GO:0019079 viral genome replication PMID:17276984
PR:000044762
NS3 (DEN2N)
capable_of GO:0017111 nucleoside-triphosphatase activity PMID:10744671
capable_of GO:0008236 serine-type peptidase activity PMID:10744671
capable_of GO:0003724 RNA helicase activity PMID:10744671
participates_in GO:0019082 viral protein processing PMID:10744671
PR:000044765
2K (DEN2N)
capable_of GO:0043495 protein-membrane adaptor activity PMID:21810535
located_in GO:0031225 anchored component of membrane PMID:21810535
participates_in GO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence PMID:17276984
PR:000044770
prM (DEN2N)
Asn-183, MOD:00160 		located_in GO:0019031 viral envelope PMID:8429301
participates_in GO:0046730 induction by virus of host immune response PMID:8429301
PR:000044766
NS4B (DEN2N)
located_in GO:0019034 viral replication complex PMID:21810535
participates_in GO:0019079 viral genome replication PMID:21810535
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0019076 viral release from host cell PR:000044759 NS2A (DEN2N)

PMID:23408612
GO:0019079 viral genome replication PR:000044758 NS1 (DEN2N)
Asn-905/Asn-982, MOD:00160
PMID:23408612
PR:000044759 NS2A (DEN2N)

PMID:23408612
PR:000044763 NS4A (DEN2N)

PMID:17276984
PR:000044766 NS4B (DEN2N)

PMID:21810535
PR:000044768 NS5 (DEN2N)

PMID:21810535
GO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence PR:000044765 2K (DEN2N)

PMID:17276984
GO:0097281 immune complex formation PR:000044758 NS1 (DEN2N)
Asn-905/Asn-982, MOD:00160
PMID:23408612
GO:0042783 evasion of host immune response PR:000044768 NS5 (DEN2N)

PMID:21810535
GO:0001510 RNA methylation PR:000044768 NS5 (DEN2N)

PMID:21810535
GO:1900005 positive regulation of serine-type endopeptidase activity PR:000044761 NS2B (DEN2N)

PMID:10744671
GO:0019068 virion assembly PR:000044759 NS2A (DEN2N)

PMID:23408612
GO:0019082 viral protein processing PR:000044762 NS3 (DEN2N)

PMID:10744671
GO:0046730 induction by virus of host immune response PR:000044770 prM (DEN2N)
Asn-183, MOD:00160
PMID:8429301
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0019034 viral replication complex PR:000044758 NS1 (DEN2N)
Asn-905/Asn-982, MOD:00160
PMID:23408612
PR:000044759 NS2A (DEN2N)

PMID:23408612
PR:000044763 NS4A (DEN2N)

PMID:17276984
PR:000044766 NS4B (DEN2N)

PMID:21810535
PR:000044768 NS5 (DEN2N)

PMID:21810535
GO:0031225 anchored component of membrane PR:000044765 2K (DEN2N)

PMID:21810535
GO:0019031 viral envelope PR:000044770 prM (DEN2N)
Asn-183, MOD:00160
PMID:8429301

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