Protein Ontology Report - hNRP1 PR:O14786 - http://purl.obolibrary.org/obo/PR_O14786

This page represents a class of proteins encompassing all the protein products of the NRP1 gene in human .

Ontology Information
PRO ID	PR:O14786 Show OBO stanza / PAF
PRO name	neuropilin-1 (human)
Synonyms	PRO-short-label: hNRP1 EXACT: CD304 (human); vascular endothelial cell growth factor 165 receptor (human) Gene-based: NRP; NRP1; VEGF165R
Definition	A neuropilin-1 that is encoded in the genome of human. [PRO:WCB, UniProtKB:O14786]
PRO Category	organism-gene
Parent	PR:000001900 neuropilin-1
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 8
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	HGNC:8004, UniProtKB:O14786

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000001900 NRP1 has_part Pfam:PF00431 CUB domain has_part Pfam:PF00629 MAM domain, meprin/A5/mu has_part Pfam:PF00754 F5/8 type C domain PR:000036635 hNRP1/iso:1/SigPep- capable_of GO:0005515 protein binding with PR:P49763-3 hPGF/iso:PlGF-2 PMID:11986311 capable_of GO:0005515 protein binding with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:11986311 capable_of GO:0005515 protein binding with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549 capable_of GO:0008201 heparin binding PMID:11986311 capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35968 hKDR PMID:16763549 has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549 PR:000036632 hNRP1/iso:1/ClvOGlyco:2 Ser-612, MOD:00213 capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding decreased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P35968 hKDR PMID:16763549 capable_of GO:0005515 protein binding increased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549 has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549 participates_in GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549 PR:000036631 hNRP1/iso:1/ClvOGlyco:1 Ser-612, MOD:00215 capable_of GO:0043184 vascular endothelial growth factor receptor 2 binding with PR:P35968 hKDR PMID:16763549 capable_of GO:0005515 protein binding increased relative to PR:000036635 hNRP1/iso:1/SigPep- with PR:P15692-4 hVEGFA/iso:VEGF165 PMID:16763549 has_part Pfam:PF00629 MAM domain, meprin/A5/mu PMID:16763549 participates_in GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549 Biological Process GO Term Protein Forms & Complexes Evidence GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PR:000036631 hNRP1/iso:1/ClvOGlyco:1 Ser-612, MOD:00215 PMID:16763549 PR:000036632 hNRP1/iso:1/ClvOGlyco:2 Ser-612, MOD:00213 PMID:16763549

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