back to PRO homepage

Protein Ontology Report - SIRT3

PR:000029756 - http://purl.obolibrary.org/obo/PR_000029756
Ontology Information
PRO ID PR:000029756 Show OBO stanza / PAF
PRO name NAD-dependent protein deacetylase sirtuin-3, mitochondrial
Synonyms
PRO-short-label: SIRT3
EXACT: SIR2-like protein 3; regulatory protein SIR2 homolog 3
Gene-based: SIR2L3
Definition A protein that is a translation product of the human SIRT3 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 0 organism-sequence 4
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q8R104-1
mSIRT3/iso:1
capable_of GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) MGI:4830236, PMID:19241369
located_in GO:0005739 mitochondrion MGI:4830236, PMID:19241369
participates_in GO:0006476 protein deacetylation MGI:4830236, PMID:19241369
PR:Q8R104-2
mSIRT3/iso:2
capable_of NOT GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) MGI:1926994, PMID:11056054
located_in GO:0005737 cytoplasm MGI:1926994, PMID:11056054
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006476 protein deacetylation PR:Q8R104-1 mSIRT3/iso:1

MGI:4830236, PMID:19241369
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:Q8R104-2 mSIRT3/iso:2

MGI:1926994, PMID:11056054
GO:0005739 mitochondrion PR:Q8R104-1 mSIRT3/iso:1

MGI:4830236, PMID:19241369

top