Protein Ontology Report - (pIRF3:pIRF7) PR:000027083 - http://purl.obolibrary.org/obo/PR_000027083

Ontology Information
PRO ID	PR:000027083 Show OBO stanza
PRO name	IRF3-P:IRF7-P complex
Synonyms	PRO-short-label: (pIRF3:pIRF7) EXACT: IRF3pIRF7p
Definition	A protein-containing complex that is composed of a heterodimer of phosphorylated IRF-3 and phosphorylated IRF-7. [PMID:18068231, PRO:CNA, TLR:AMM]
Comment	Requested by=TLR.
PRO Category	complex
Parent	GO:0032991 protein-containing complex
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms complex 1 organism-complex 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All complex organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000027084 PR:000027082 interferon regulatory factor 7 isoform 1 phosphorylated 1 (human) hIRF7/iso:1/Phos:1 An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046. [PMID:10893229, PMID:14517278, TLR:AMM] 1 PR:000045489 interferon regulatory factor 3 isoform 1 phosphorylated 2 (human) hIRF3/iso:1/Phos:2 An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047. [PRO:CNA, Reactome:R-HSA-936418] 1

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