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Protein Ontology Report - RARA

PR:000013736 - http://purl.obolibrary.org/obo/PR_000013736
Ontology Information
PRO ID PR:000013736 Show OBO stanza / PAF
PRO name retinoic acid receptor alpha
Synonyms
PRO-short-label: RARA
EXACT: RAR-alpha; RARalpha; nuclear receptor subfamily 1 group B member 1
Gene-based: NR1B1
Definition A protein that is a translation product of the human RARA gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 2 organism-sequence 7
modification 1 organism-modification 3
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P11416-1
mRARA/iso:1
capable_of GO:0043565 sequence-specific DNA binding PMID:17928865
capable_of GO:0003677 DNA binding PMID:15528198
capable_of GO:0003677 DNA binding PMID:14980219
capable_of GO:0004879 nuclear receptor activity PMID:15528198
capable_of GO:0004879 nuclear receptor activity PMID:15322135
capable_of GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding MGI:3053708, PMID:1655807
capable_of GO:0003700 DNA-binding transcription factor activity PMID:8152920
capable_of GO:0003700 DNA-binding transcription factor activity PMID:15528198
capable_of GO:0005515 protein binding with PR:Q64127 mTRIM24 PMID:8978696
capable_of GO:0005515 protein binding with PR:Q8CBD1 mNRIP1 PMID:10531331
located_in GO:0005634 nucleus with CHEBI:15367 PMID:12079996
located_in GO:0005737 cytoplasm PMID:12079996
located_in GO:0043025 neuronal cell body MGI:3803427, PMID:18495661
located_in GO:0030425 dendrite MGI:3803427, PMID:18495661
participates_in GO:0045947 negative regulation of translational initiation MGI:3803427, PMID:18495661
participates_in GO:0045892 negative regulation of transcription, DNA-templated PMID:11641275
participates_in GO:0006355 regulation of transcription, DNA-templated PMID:12079996
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II PMID:8152920
participates_in GO:0006355 regulation of transcription, DNA-templated PMID:12101409
PR:P11416
mRARA
capable_of GO:0043565 sequence-specific DNA binding PMID:7823919
participates_in GO:0055012 ventricular cardiac muscle cell differentiation PMID:9428411
participates_in GO:0032526 response to retinoic acid PMID:11222375
participates_in GO:0007283 spermatogenesis PMID:8394014
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II PMID:7566114
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II PMID:7823919
participates_in GO:0001657 ureteric bud development PMID:12195422
participates_in GO:0010629 negative regulation of gene expression PMID:18026104
participates_in GO:0008284 positive regulation of cell population proliferation PMID:18026104
participates_in GO:0030852 regulation of granulocyte differentiation PMID:11222375
participates_in GO:0045944 positive regulation of transcription by RNA polymerase II PMID:15766748
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007283 spermatogenesis PR:P11416 mRARA

PMID:8394014
GO:0008284 positive regulation of cell population proliferation PR:P11416 mRARA

PMID:18026104
GO:0000122 negative regulation of transcription by RNA polymerase II PR:P11416 mRARA

PMID:7566114
PR:P11416-1 mRARA/iso:1

PMID:8152920
GO:0010629 negative regulation of gene expression PR:P11416 mRARA

PMID:18026104
GO:0006355 regulation of transcription, DNA-templated PR:P11416-1 mRARA/iso:1

PMID:12079996
PR:P11416-1 mRARA/iso:1

PMID:12101409
GO:0045944 positive regulation of transcription by RNA polymerase II PR:P11416 mRARA

PMID:7823919
PR:P11416 mRARA

PMID:15766748
GO:0032526 response to retinoic acid PR:P11416 mRARA

PMID:11222375
GO:0030852 regulation of granulocyte differentiation PR:P11416 mRARA

PMID:11222375
GO:0001657 ureteric bud development PR:P11416 mRARA

PMID:12195422
GO:0055012 ventricular cardiac muscle cell differentiation PR:P11416 mRARA

PMID:9428411
GO:0045947 negative regulation of translational initiation PR:P11416-1 mRARA/iso:1

MGI:3803427, PMID:18495661
GO:0045892 negative regulation of transcription, DNA-templated PR:P11416-1 mRARA/iso:1

PMID:11641275
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:P11416-1 mRARA/iso:1

with CHEBI:15367 		PMID:12079996
GO:0005737 cytoplasm PR:P11416-1 mRARA/iso:1

PMID:12079996
GO:0030425 dendrite PR:P11416-1 mRARA/iso:1

MGI:3803427, PMID:18495661
GO:0043025 neuronal cell body PR:P11416-1 mRARA/iso:1

MGI:3803427, PMID:18495661

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