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Protein Ontology Report - ADAR

PR:000003745 - http://purl.obolibrary.org/obo/PR_000003745
Ontology Information
PRO ID PR:000003745 Show OBO stanza / PAF
PRO name double-stranded RNA-specific adenosine deaminase
Synonyms
PRO-short-label: ADAR
BROAD: p136
EXACT: 136 kDa double-stranded RNA-binding protein; DRADA; IFI-4; K88DSRBP; RNA adenosine deaminase 1; interferon-inducible protein 4
Gene-based: ADAR1; DSRAD; G1P1; IFI4
Definition A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 5 organism-sequence 10
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q99MU3-4
mADAR/iso:4
capable_of GO:0003726 double-stranded RNA adenosine deaminase activity MGI:5515381, PMID:12954622
PR:Q99MU3-1
mADAR/iso:1
capable_of GO:0003726 double-stranded RNA adenosine deaminase activity MGI:5515381, PMID:12954622
located_in GO:0005737 cytoplasm MGI:5515381, PMID:12954622
participates_in GO:0001701 in utero embryonic development MGI:4939544, PMID:21173229
participates_in GO:0051607 defense response to virus MGI:4939544, PMID:21173229
participates_in GO:0045071 negative regulation of viral genome replication MGI:4939544, PMID:21173229
PR:Q99MU3-2
mADAR/iso:2
capable_of GO:0003726 double-stranded RNA adenosine deaminase activity MGI:5515381, PMID:12954622
located_in GO:0005737 cytoplasm MGI:5515381, PMID:12954622
PR:Q99MU3-3
mADAR/iso:3
capable_of GO:0003726 double-stranded RNA adenosine deaminase activity MGI:5515381, PMID:12954622
located_in GO:0005730 nucleolus MGI:5515381, PMID:12954622
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0001701 in utero embryonic development PR:Q99MU3-1 mADAR/iso:1

MGI:4939544, PMID:21173229
GO:0051607 defense response to virus PR:Q99MU3-1 mADAR/iso:1

MGI:4939544, PMID:21173229
GO:0045071 negative regulation of viral genome replication PR:Q99MU3-1 mADAR/iso:1

MGI:4939544, PMID:21173229
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:Q99MU3-1 mADAR/iso:1

MGI:5515381, PMID:12954622
PR:Q99MU3-2 mADAR/iso:2

MGI:5515381, PMID:12954622
GO:0005730 nucleolus PR:Q99MU3-3 mADAR/iso:3

MGI:5515381, PMID:12954622

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