back to PRO homepage

Protein Ontology Report - leukocyte granule-associated proteinase

PR:000003505 - http://purl.obolibrary.org/obo/PR_000003505
Ontology Information
PRO ID PR:000003505 Show OBO stanza
PRO name leukocyte granule-associated proteinase
Definition A trypsin that is a serine protease of the granules from mast cells, cytotoxic T lymphocytes and/or natural killer cells. Leukocyte granule-associated proteinase is a component of the immune system that protect higher organisms against viral infection and cellular transformation. Members of this class have features that are strongly conserved including: consensus sequences at their N-termini and around the three catalytic residues, activation from zymogenic forms, and conserved disulphide bridges. [PMID:11790262, PMID:7952649, PMID:8929545]
PRO Category family
Parent PR:000027795 trypsin
Term Hierarchy Visualization DAG     OLS     Cytoscape

top