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Protein Ontology Report - THRA

PR:000003428 - http://purl.obolibrary.org/obo/PR_000003428
Ontology Information
PRO ID PR:000003428 Show OBO stanza / PAF
PRO name thyroid hormone receptor alpha
Synonyms
PRO-short-label: THRA
EXACT: EAR-7; TR-alpha; V-erbA-related protein 7; c-erbA-1; c-erbA-alpha; nuclear receptor subfamily 1 group A member 1
Gene-based: EAR7; ERBA1; NR1A1; THRA1; THRA2
Definition A protein that is a translation product of the human THRA gene or a 1:1 ortholog thereof. [MGI:98742, PRO:HJD]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 4 organism-sequence 10
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P63058-4
mTHRA/iso:Alpha-deltaE6
located_in GO:0005737 cytoplasm MGI:3619869, PMID:16322094
participates_in GO:0042994 cytoplasmic sequestering of transcription factor MGI:3619869, PMID:16322094
participates_in GO:0010831 positive regulation of myotube differentiation MGI:3619869, PMID:16322094
PR:P63058
mTHRA
participates_in GO:0009887 animal organ morphogenesis PMID:9927422
participates_in GO:0001503 ossification PMID:9927422
participates_in GO:0007611 learning or memory PMID:17129617
participates_in GO:0001502 cartilage condensation PMID:9250685
participates_in GO:0008016 regulation of heart contraction PMID:15240882
participates_in GO:0008016 regulation of heart contraction PMID:9430637
participates_in GO:0001503 ossification PMID:9250685
PR:P63058-1
mTHRA/iso:Alpha-2
capable_of GO:0005515 protein binding with PR:Q924W6 mTRIM66 PMID:15322135
capable_of GO:0005515 protein binding with PR:Q61645 mHR PMID:11641275
participates_in GO:0045892 negative regulation of transcription, DNA-templated PMID:11641275, PMID:15062575
PR:P63058-2
mTHRA/iso:Alpha-1
capable_of GO:0002153 steroid receptor RNA activator RNA binding MGI:3050934, PMID:15180993
capable_of GO:0003727 single-stranded RNA binding MGI:3050934, PMID:15180993
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0001502 cartilage condensation PR:P63058 mTHRA

PMID:9250685
GO:0042994 cytoplasmic sequestering of transcription factor PR:P63058-4 mTHRA/iso:Alpha-deltaE6

MGI:3619869, PMID:16322094
GO:0007611 learning or memory PR:P63058 mTHRA

PMID:17129617
GO:0045892 negative regulation of transcription, DNA-templated PR:P63058-1 mTHRA/iso:Alpha-2

PMID:11641275, PMID:15062575
GO:0008016 regulation of heart contraction PR:P63058 mTHRA

PMID:15240882
PR:P63058 mTHRA

PMID:9430637
GO:0009887 animal organ morphogenesis PR:P63058 mTHRA

PMID:9927422
GO:0010831 positive regulation of myotube differentiation PR:P63058-4 mTHRA/iso:Alpha-deltaE6

MGI:3619869, PMID:16322094
GO:0001503 ossification PR:P63058 mTHRA

PMID:9927422
PR:P63058 mTHRA

PMID:9250685
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:P63058-4 mTHRA/iso:Alpha-deltaE6

MGI:3619869, PMID:16322094

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