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Protein Ontology Report - SUFU

PR:000003324 - http://purl.obolibrary.org/obo/PR_000003324
Ontology Information
PRO ID PR:000003324 Show OBO stanza / PAF
PRO name suppressor of fused homolog
Synonyms
PRO-short-label: SUFU
EXACT: SUFUH
Gene-based: UNQ650/PRO1280
Definition A protein that is a translation product of the human SUFU gene or a 1:1 ortholog thereof. [MGI:1345643, PRO:HJD]
PRO Category gene
Parent PR:000000001 protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 3 organism-sequence 7
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9Z0P7-1
mSUFU/iso:1
capable_of GO:0005515 protein binding with PR:P47806 mGLI1 MGI:1861566, PMID:10920228
capable_of GO:0005515 protein binding with PR:Q61602 mGLI3 MGI:1861566, PMID:10920228
located_in GO:0005737 cytoplasm MGI:3608582, PMID:16316410
located_in GO:0005634 nucleus MGI:3692156, PMID:16254602
located_in GO:0005929 cilium MGI:3692156, PMID:16254602
PR:Q9Z0P7
mSUFU
participates_in GO:0043588 skin development PMID:16459298
participates_in GO:0021513 spinal cord dorsal/ventral patterning PMID:16459298
participates_in GO:0045879 negative regulation of smoothened signaling pathway PMID:16459298
PR:Q9Z0P7-4
mSUFU/iso:4
capable_of GO:0005515 protein binding with PR:P47806 mGLI1 MGI:1346364, PMID:10531011
capable_of GO:0005515 protein binding with PR:Q0VGT2 mGLI2 MGI:1346364, PMID:10531011
capable_of GO:0005515 protein binding with PR:P10071 hGLI3 MGI:1346364, PMID:10531011
located_in GO:0005737 cytoplasm MGI:1346364, PMID:10531011
participates_in GO:0000122 negative regulation of transcription by RNA polymerase II MGI:1346364, PMID:10531011
participates_in GO:0045879 negative regulation of smoothened signaling pathway MGI:1346364, PMID:10531011
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0000122 negative regulation of transcription by RNA polymerase II PR:Q9Z0P7-4 mSUFU/iso:4

MGI:1346364, PMID:10531011
GO:0043588 skin development PR:Q9Z0P7 mSUFU

PMID:16459298
GO:0045879 negative regulation of smoothened signaling pathway PR:Q9Z0P7 mSUFU

PMID:16459298
PR:Q9Z0P7-4 mSUFU/iso:4

MGI:1346364, PMID:10531011
GO:0021513 spinal cord dorsal/ventral patterning PR:Q9Z0P7 mSUFU

PMID:16459298
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q9Z0P7-1 mSUFU/iso:1

MGI:3692156, PMID:16254602
GO:0005737 cytoplasm PR:Q9Z0P7-1 mSUFU/iso:1

MGI:3608582, PMID:16316410
PR:Q9Z0P7-4 mSUFU/iso:4

MGI:1346364, PMID:10531011
GO:0005929 cilium PR:Q9Z0P7-1 mSUFU/iso:1

MGI:3692156, PMID:16254602

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