| PRO ID |
PR:000003281
Show OBO stanza
|
| PRO name |
interferon regulatory factor 7 isoform 1 phosphorylated 1 |
| Synonyms |
| PRO-short-label: |
IRF7/iso:1/Phos:1 |
| EXACT: |
IRF-7 active form; IRF-7 phosphorylated; phospho IRF7 |
|
| Definition |
An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046.
[PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM]
|
| Comment |
Requested by=TLR. |
| PRO Category |
modification |
| Parent |
PR:000003280 interferon regulatory factor 7 isoform 1 phosphorylated form |
| Term Hierarchy Visualization |
 DAG
 OLS
Cytoscape
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