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Protein Ontology Report - BCL2L1

PR:000002308 - http://purl.obolibrary.org/obo/PR_000002308
Ontology Information
PRO ID PR:000002308 Show OBO stanza / PAF
PRO name Bcl-2-like protein 1
Synonyms
PRO-short-label: BCL2L1
EXACT: Bcl2-L-1; apoptosis regulator Bcl-X
Gene-based: BCL2L; BCLX
Definition A Bcl-2-like apoptosis inhibitor that is a translation product of the human BCL2L1 gene or a 1:1 ortholog thereof. [PRO:WCB]
PRO Category gene
Parent PR:000002186 Bcl-2-like apoptosis inhibitor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 4
sequence 5 organism-sequence 12
modification 0 organism-modification 1
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q64373-1
mBCL2L1/iso:Bcl-X(L)
associated_with_disease_progression DOID:162 cancer PMID:16403219
capable_of GO:0046982 protein heterodimerization activity with PR:Q07813 mBAX MGI:82784, PMID:8798452
capable_of GO:0005515 protein binding with PR:O08734 mBAK1 MGI:3804133, PMID:16705087
participates_in GO:0043066 negative regulation of apoptotic process MGI:81233, PMID:8798158
participates_in GO:0043066 negative regulation of apoptotic process MGI:69011, PMID:7607090
PR:Q64373-2
mBCL2L1/iso:Bcl-X(S)
participates_in GO:0043065 positive regulation of apoptotic process MGI:81233, PMID:8798158
PR:Q07817-1
hBCL2L1/iso:1
capable_of GO:0005515 protein binding with PR:000028379 hBID/iso:1/Clv:1 PMID:11583631
capable_of GO:0005515 protein binding with PR:Q16611 hBAK1 PMID:8596636
capable_of GO:0005515 protein binding decreased relative to PR:000002843 BAD/iso:1/UnMod with PR:000026167 mBAD/iso:1/Phos:1 PMID:10949026
capable_of GO:0005515 protein binding with PR:O54918 mBCL2L11 PMID:11583631
capable_of NOT GO:0005515 protein binding with PR:000026133 mBAD/iso:1/Phos:2 PMID:10949026
capable_of GO:0005515 protein binding with PR:Q61337 mBAD PMID:11583631
capable_of GO:0005515 protein binding with PR:Q92934-1 hBAD/iso:1 PMID:10949026
capable_of GO:0005515 protein binding with PR:Q07812 hBAX PMID:8596636
participates_in GO:0043066 negative regulation of apoptotic process PMID:8596636
participates_in GO:0006915 apoptotic process PMID:10949026
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0043066 negative regulation of apoptotic process PR:Q07817-1 hBCL2L1/iso:1

PMID:8596636
PR:Q64373-1 mBCL2L1/iso:Bcl-X(L)

MGI:81233, PMID:8798158
PR:Q64373-1 mBCL2L1/iso:Bcl-X(L)

MGI:69011, PMID:7607090
GO:0006915 apoptotic process PR:Q07817-1 hBCL2L1/iso:1

PMID:10949026
GO:0043065 positive regulation of apoptotic process PR:Q64373-2 mBCL2L1/iso:Bcl-X(S)

MGI:81233, PMID:8798158

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