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Protein Ontology Report - KCNC1/iso:Long/Phos:1

PR:000000992 - http://purl.obolibrary.org/obo/PR_000000992
Ontology Information
PRO ID PR:000000992 Show OBO stanza
PRO name voltage-gated potassium channel KCNC1 isoform Long phosphorylated 1
Synonyms
PRO-short-label: KCNC1/iso:Long/Phos:1
EXACT: KCNC1/iso:2/Phos:1; voltage-gated potassium channel KCNC1 isoform 2 phosphorylated 1
Definition A voltage-gated potassium channel KCNC1 isoform Long phosphorylated form in which the phosphorylation occurs by the action of PKC at the Ser residue within the DSKL motif located in the C-terminal tail. In resting neurons, basal phosphorylation at this site decreases Kv3.1 channel current, reducing neuronal ability to follow high frequency stimulation. Example: UniProtKB:P25122-1, Ser-503, MOD:00046. [PMID:16595659]
PRO Category modification
Parent PR:000000986 voltage-gated potassium channel KCNC1 isoform Long phosphorylated form
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Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

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