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Protein Ontology Report - KCNA7/iso:1

PR:000000979 - http://purl.obolibrary.org/obo/PR_000000979
Ontology Information
PRO ID PR:000000979 Show OBO stanza
PRO name voltage-gated potassium channel subunit KCNA7 isoform 1
Synonyms
PRO-short-label: KCNA7/iso:1
RELATED: Kv1.7L; Potassium voltage-gated channel subfamily A member 7 isoform 1
Definition A voltage-gated potassium channel subunit KCNA7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q17ST2-1 or a 1:1 ortholog thereof. [PRO:CNA, PRO:DAN]
Comment Note: This isoform contains an Hx20CxCC motif--resembling a metal coordination motif--in the N-terminal region. The N terminus appears to be a key component in the redox sensitivity of Kv1.7 channel inactivation. This form contributes to channels that inactivate fast and are sensitive to redox modulation.
PRO Category sequence
Parent PR:000000814 voltage-gated potassium channel subunit KCNA7
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Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

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