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Protein Ontology Report - KCNA10

PR:000000809 - http://purl.obolibrary.org/obo/PR_000000809
Ontology Information
PRO ID PR:000000809 Show OBO stanza / PAF
PRO name voltage-gated potassium channel subunit KCNA10
Synonyms
PRO-short-label: KCNA10
EXACT: voltage-gated potassium channel subunit Kv1.8
Definition A shaker-related voltage-gated potassium channel alpha subunit that is a translation product of the human KCNA10 gene or a 1:1 ortholog thereof. It is a subunit of the Kv1.8 channel is a delayed rectifier channel that may be involved in regulating the tone of renal vascular smooth muscle and may also participate in the cardiac action potential. It is regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. It can coassemble with other Kv1 subunits. [PMID:10836990]
PRO Category gene
Parent PR:000000709 shaker-related voltage-gated potassium channel alpha subunit
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 1
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q16322-1
hKCNA10/iso:1
capable_of GO:0005251 delayed rectifier potassium channel activity PMID:10836990
capable_of GO:0005221 intracellular cyclic nucleotide activated cation channel activity PMID:10836990, PMID:9177773
part_of GO:0008076 voltage-gated potassium channel complex PMID:12060596

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