PRO ID |
PR:000000563
Show OBO stanza
|
PRO name |
Rho-associated protein kinase 1 isoform 1 cleaved 1 |
Synonyms |
PRO-short-label: |
ROCK1/iso:1/Clv:1 |
EXACT: |
constitutively active ROCK-1 |
|
Definition |
A Rho-associated protein kinase 1 isoform 1 that has been processed by caspase-3 downstream the sequence motif DETD, removing the inhibitory C-terminus.
[PMID:11283607, PMID:16983089]
|
Comment |
Note: This form has been found significantly elevated in mouse myopathy model and human heart failure patients. |
PRO Category |
modification |
Parent |
PR:000000307 Rho-associated protein kinase 1 isoform 1 |
Term Hierarchy Visualization |
DAG
OLS
Cytoscape
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