back to PRO homepage

Protein Ontology Report - SMAD5

PR:000000372 - http://purl.obolibrary.org/obo/PR_000000372
Ontology Information
PRO ID PR:000000372 Show OBO stanza / PAF
PRO name smad5
Synonyms
PRO-short-label: SMAD5
EXACT: Dwf-C; JV5-1; MAD homolog 5; SMAD 5; SMAD family member 5; Smad5; dwarfin-C; mothers against DPP homolog 5
Gene-based: MADH5
Definition A BMP receptor-regulated smad protein that is a translation product of the human SMAD5 gene or a 1:1 ortholog thereof. [PMID:10708949]
PRO Category gene
Parent PR:000000038 BMP receptor-regulated smad protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 5
sequence 2 organism-sequence 3
modification 4 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036562
hSMAD5/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046 		capable_of GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135
participates_in GO:0030509 BMP signaling pathway PMID:8637600
PR:000036563
mSMAD5/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046 		located_in GO:0005634 nucleus PMID:10504300, PMID:9759503
participates_in GO:0030509 BMP signaling pathway PMID:16522160
PR:P97454-1
mSMAD5/iso:1
located_in GO:0005737 cytoplasm PMID:10504300
participates_in GO:0030509 BMP signaling pathway PMID:16522160, PMID:16765933
participates_in GO:0007165 signal transduction PMID:16765933
PR:000029962
hSMAD5/iso:2
capable_of NOT GO:0046332 SMAD binding PMID:10845932
PR:Q99717-1
hSMAD5/iso:1
capable_of GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:8673135
participates_in GO:0030509 BMP signaling pathway PMID:8673135
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030509 BMP signaling pathway PR:000036562 hSMAD5/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:8637600
PR:000036563 mSMAD5/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:16522160
PR:P97454-1 mSMAD5/iso:1

PMID:16522160, PMID:16765933
PR:Q99717-1 hSMAD5/iso:1

PMID:8673135
GO:0007165 signal transduction PR:P97454-1 mSMAD5/iso:1

PMID:16765933
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000036563 mSMAD5/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:10504300, PMID:9759503
GO:0005737 cytoplasm PR:P97454-1 mSMAD5/iso:1

PMID:10504300

top