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Protein Ontology Report - SMURF2

PR:000000362 - http://purl.obolibrary.org/obo/PR_000000362
Ontology Information
PRO ID PR:000000362 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SMURF2
Synonyms
PRO-short-label: SMURF2
EXACT: HECT-type E3 ubiquitin transferase SMURF2; SMAD ubiquitination regulatory factor 2; SMAD-specific E3 ubiquitin-protein ligase 2; smad ubiquitination regulatory factor 2
Definition A smad ubiquitination regulatory factor that is a translation product of the human SMURF2 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000127 smad ubiquitination regulatory factor
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 3
sequence 1 organism-sequence 3
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9HAU4
hSMURF2
capable_of GO:0005515 protein binding with PR:Q9Y3C5 hRNF11 PMID:14755250
capable_of GO:0004842 ubiquitin-protein transferase activity PMID:14755250
participates_in GO:0017015 regulation of transforming growth factor beta receptor signaling pathway PMID:11016919, PMID:11158580, PMID:11163210, PMID:15862290
participates_in GO:0006511 ubiquitin-dependent protein catabolic process PMID:14755250
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006511 ubiquitin-dependent protein catabolic process PR:Q9HAU4 hSMURF2

PMID:14755250
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway PR:Q9HAU4 hSMURF2

PMID:11016919, PMID:11158580, PMID:11163210, PMID:15862290

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