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Protein Ontology Report - BMP7

PR:000000168 - http://purl.obolibrary.org/obo/PR_000000168
Ontology Information
PRO ID PR:000000168 Show OBO stanza / PAF
PRO name bone morphogenetic protein 7
Synonyms
PRO-short-label: BMP7
EXACT: BMP-7; OP-1; eptotermin alfa; osteogenic protein 1
Gene-based: OP1
Definition A bone morphogenetic protein that is a translation product of the human BMP7 gene or a 1:1 ortholog thereof. [PRO:CNA]
PRO Category gene
Parent PR:000000034 bone morphogenetic protein
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 2
sequence 1 organism-sequence 2
modification 6 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036517
hBMP7/iso:1/mature/NGlyco:1
Asn-372, MOD:00160 		capable_of GO:0042803 protein homodimerization activity PMID:15929982, PMID:8570652
capable_of GO:0005102 signaling receptor binding PMID:9872992
located_in GO:0005615 extracellular space PMID:15047707, PMID:15929982
PR:000036516
mBMP7/iso:1/mature
capable_of GO:0005515 protein binding PMID:12741987
located_in GO:0005615 extracellular space PMID:12741987
participates_in GO:0007411 axon guidance PMID:12741987
PR:P23359
mBMP7
participates_in GO:0042475 odontogenesis of dentin-containing tooth PMID:15525533
participates_in GO:0048754 branching morphogenesis of an epithelial tube PMID:15831470
participates_in GO:0009887 animal organ morphogenesis PMID:7590254
participates_in GO:0035239 tube morphogenesis PMID:15831470
participates_in GO:0007435 salivary gland morphogenesis PMID:11731698
PR:000036519
hBMP7/iso:1/mature/NGlyco:2
Asn-372, MOD:00160 		capable_of NOT GO:0005102 signaling receptor binding PMID:15929982
located_in GO:0005615 extracellular space PMID:15929982
PR:000036518
mBMP7/iso:1/mature/NGlyco:1
Asn-371, MOD:00160 		participates_in GO:0030509 BMP signaling pathway PMID:14623234
PR:P18075-1
hBMP7/iso:1
capable_of GO:0005515 protein binding PMID:12805376
located_in GO:0005794 Golgi apparatus PMID:12805376
participates_in GO:0001501 skeletal system development PMID:2357959
PR:P23359-1
mBMP7/iso:1
participates_in GO:0030509 BMP signaling pathway PMID:14623234
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007435 salivary gland morphogenesis PR:P23359 mBMP7

PMID:11731698
GO:0030509 BMP signaling pathway PR:000036518 mBMP7/iso:1/mature/NGlyco:1
Asn-371, MOD:00160
PMID:14623234
PR:P23359-1 mBMP7/iso:1

PMID:14623234
GO:0009887 animal organ morphogenesis PR:P23359 mBMP7

PMID:7590254
GO:0007411 axon guidance PR:000036516 mBMP7/iso:1/mature

PMID:12741987
GO:0048754 branching morphogenesis of an epithelial tube PR:P23359 mBMP7

PMID:15831470
GO:0042475 odontogenesis of dentin-containing tooth PR:P23359 mBMP7

PMID:15525533
GO:0001501 skeletal system development PR:P18075-1 hBMP7/iso:1

PMID:2357959
GO:0035239 tube morphogenesis PR:P23359 mBMP7

PMID:15831470
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005794 Golgi apparatus PR:P18075-1 hBMP7/iso:1

PMID:12805376
GO:0005615 extracellular space PR:000036516 mBMP7/iso:1/mature

PMID:12741987
PR:000036517 hBMP7/iso:1/mature/NGlyco:1
Asn-372, MOD:00160
PMID:15047707, PMID:15929982
PR:000036519 hBMP7/iso:1/mature/NGlyco:2
Asn-372, MOD:00160
PMID:15929982

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