PMID: 21429240

HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase.

Abstract

BACKGROUND: Human Cytomegalovirus (HCMV) has been implicated in the acceleration of vascular disease and chronic allograft rejection. Recently, the virus has been associated with glioblastoma and other tumors. We have previously shown that the

PTM Type Substrate Site PTM Enzyme Source
Phosphorylation iPTM:Q14289 (PTK2B)
PRO
Y402 RLIMS-P