iPTMnet Report for Q9Z2A0 (Pdpk1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Z2A0 / PDPK1_MOUSE
Protein Name 3-phosphoinositide-dependent protein kinase 1
Gene Name Name: Pdpk1
Synonyms:Pdk1;
Organism Mus musculus (Mouse)

PRO ID PR:Q9Z2A0
DAG View
PRO Name 3-phosphoinositide-dependent protein kinase 1 (mouse)
Definition A 3-phosphoinositide-dependent protein kinase 1 that is encoded in the genome of mouse.
Short Label mPDPK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Z2A0 (Pdpk1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R3 Methylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S38 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
T55 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
T63 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S163 Phosphorylation phospho.ELM   PhosphoSitePlus 16751192
S234 Phosphorylation PhosphoSitePlus
S244 Phosphorylation Q9Z2A0 (Pdpk1) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17242355, 12923190, 21183079, ...14623982, 17114649, 15345747
T248 Phosphorylation PhosphoSitePlus
Y251 Phosphorylation PhosphoSitePlus
K260 Ubiquitination PhosphoSitePlus
K299 Sumoylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K307 Acetylation PhosphoSitePlus   UniProt 23806337
S399 Phosphorylation Q9Z2A0 (Pdpk1) phospho.ELM   PhosphoSitePlus 12923190
S504 Phosphorylation Q02111 (Prkcq) PhosphoSitePlus   UniProt 19047061
T516 Phosphorylation Q9Z2A0 (Pdpk1) phospho.ELM   PhosphoSitePlus   RLIMS-P 11877406, 12923190
S532 Phosphorylation Q02111 (Prkcq) PhosphoSitePlus   UniProt 19047061


Q9Z2A0 (Pdpk1) as PTM Enzyme



Substrate Site Score Source PMID
P05132 (Prkaca) T198 PhosphoSitePlus 9707564
P18654 (Rps6ka3) S227 PhosphoSitePlus 10480933
P18654 (Rps6ka3) S369 PhosphoSitePlus 10480933
P18654 (Rps6ka3) S386 PhosphoSitePlus 10480933
P18654 (Rps6ka3) T577 PhosphoSitePlus 10480933
P31750 (Akt1) T308 PhosphoSitePlus 19047061, 12682057
Q9Z2A0 (Pdpk1) S244 PhosphoSitePlus 12923190
Q9Z2A0 (Pdpk1) S399 PhosphoSitePlus 12923190
Q9Z2A0 (Pdpk1) T516 PhosphoSitePlus 12923190


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:Q2VEB4 (mAKAP6/iso:alpha) Interaction PR:Q9Z2A0 (mPDPK1) PRO 16337591