Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6L7 / TLL2_HUMAN
Protein Name Tolloid-like protein 2 precursor
Gene Name Name: TLL2
Synonyms:KIAA0932;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6L7
DAG View
PRO Name tolloid-like protein 2 (human)
Definition A tolloid-like protein 2 that is encoded in the genome of human.
Short Label hTLL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6L7 (TLL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T87 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
T155 Phosphorylation PhosphoSitePlus
N171 N-Glycosylation GlyGen 29741879
T327 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K613 Ubiquitination PhosphoSitePlus
S716 Phosphorylation PhosphoSitePlus
T719 Phosphorylation PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
T899 Phosphorylation PhosphoSitePlus
T989 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K613 R613 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S716 F716 Biomuta DOID:4159 / skin cancer [ cosmic ]
T899 I899 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]