Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6G9 / DC1L1_HUMAN
Protein Name Cytoplasmic dynein 1 light intermediate chain 1
Gene Name Name: DYNC1LI1
Synonyms:DNCLI1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6G9
DAG View
PRO Name cytoplasmic dynein 1 light intermediate chain 1 (human)
Definition A cytoplasmic dynein 1 light intermediate chain 1 that is encoded in the genome of human.
Short Label hDYNC1LI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6G9 (DYNC1LI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
S57 Phosphorylation HPRD 20068231
K68 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
Y93 Phosphorylation PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K95 Acetylation PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
R111 Methylation PhosphoSitePlus
Y197 Phosphorylation PhosphoSitePlus
S207 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 18212344, 20230923, 19229290, 20058876, 18220336, 19664994, 19664995, 18452278, 19651622, 18669648, 24275569, 16565220, 19690332, 20068231, 17081983
T213 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 24778311
S215 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K310 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
S398 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19229290, 18691976, 23186163, ...20068231
S405 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...19229290, 18669648, 20068231, 17924679
T408 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19229290, ...18669648, 20068231, 17924679
R411 Methylation PhosphoSitePlus
S412 O-Glycosylation GlyGen 23301498, 32938750, 34725712, ...28510447, 29351928, 31492838, 31373491, 32119511, 35254053, 34229054, 29237092
S412 Phosphorylation PhosphoSitePlus   UniProt 23186163
S414 Phosphorylation HPRD   PhosphoSitePlus 20068231
S415 Phosphorylation PhosphoSitePlus
S419 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 18669648, 20068231, ...17924679
S421 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 23186163, ...18767875, 20058876, 19007248, 19691289, 19664995, 17322306, 18669648, 19651622, 19415658, 20068231, 17924679
S427 Phosphorylation PhosphoSitePlus   UniProt 23186163
K428 Acetylation PhosphoSitePlus
K429 Acetylation PhosphoSitePlus
K435 Methylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
T439 Phosphorylation PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
K454 Ubiquitination PhosphoSitePlus
T456 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S458 O-Glycosylation GlyGen 23301498, 28510447, 34725712, ...29351928, 31492838, 31373491, 32119511, 35254053, 34229054
S458 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S465 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S468 O-Glycosylation GlyGen 23301498, 28510447, 34725712, ...29351928, 31492838, 31373491, 32119511, 35254053, 34229054
S468 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S477 Phosphorylation PhosphoSitePlus
S478 Phosphorylation PhosphoSitePlus
S483 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T484 Phosphorylation HPRD   phospho.ELM 18669648
S487 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
T508 O-Glycosylation GlyGen 23301498, 28510447, 34725712, ...29351928, 31492838, 31373491, 32119511, 35254053, 34229054
T508 Phosphorylation HPRD   PhosphoSitePlus 19664995
S510 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...18691976, 19664994, 19664995, 19651622, 17322306, 18669648, 24275569, 19690332, 20068231
T512 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 19690332, ...20068231
T513 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 18212344, ...18452278, 19651622, 18669648, 19690332, 15345747, 19415658, 20068231
T515 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18212344, 18691976, ...19651622, 18452278, 17322306, 18669648, 19690332, 19415658, 20068231, 17081983
S516 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 22028470, ...23186163, 17081983, 18691976, 18767875, 15302935, 19664995, 18452278, 19651622, 19664994, 18669648, 19690332, 18707149, 19767751, 15345747, 19415658, 20068231
S516 Phosphorylation P28482 (MAPK1) neXtProt 19767751, 22028470
T518 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648, 20068231
S523 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S207 F207 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S381 F381 Biomuta DOID:4159 / skin cancer [ cosmic ]
S419 N419 Biomuta DOID:363 / uterine cancer [ icgc ]
K429 Q429 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S468 N468 Biomuta DOID:4159 / skin cancer [ cosmic ]
S487 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T512 A512 Biomuta DOID:1324 / lung cancer [ cosmic ]
T515 A515 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S516 F516 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S523 F523 Biomuta DOID:4159 / skin cancer [ cosmic ]