iPTMnet Report for Q9Y6F6 (IRAG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y6F6 / IRAG1_HUMAN
Protein Name Inositol 1,4,5-triphosphate receptor associated 1
Gene Name Name: IRAG1
Synonyms:IRAG,JAW1L,MRVI1;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y6F6
DAG View
PRO Name inositol 1,4,5-triphosphate receptor associated 1 (human)
Definition An inositol 1,4,5-triphosphate receptor associated 1 that is encoded in the genome of human.
Short Label hIRAG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y6F6 (IRAG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S162 Phosphorylation PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S191 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S197 Phosphorylation PhosphoSitePlus
S199 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus   UniProt 16990611, 24275569
S389 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K417 Acetylation PhosphoSitePlus
K421 Acetylation PhosphoSitePlus
K424 Acetylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S657 Phosphorylation Q13976 (PRKG1) neXtProt 16990611
S676 Phosphorylation PhosphoSitePlus   UniProt 16990611
S689 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16990611, 11309393
S726 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S657 Phosphorylation PRO 16990611
S670 Phosphorylation PRO 16990611


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000026855 (hIRAG1/iso:1/Phos:1) pS657,pS670 PRO 16990611


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S189 R189 Biomuta DOID:3571 / liver cancer [ cosmic ]
S199 I199 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S312 N312 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S386 F386 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S657 * Biomuta DOID:10283 / prostate cancer [ cosmic ]