iPTMnet Report for Q9Y6E7 (SIRT4)
Protein Information
| UniProt AC / UniProt ID | Q9Y6E7 / SIR4_HUMAN |
| Protein Name | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial precursor |
| Gene Name | Name: SIRT4 Synonyms:SIR2L4; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y6E7 |
| PRO Name | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (human) |
| Definition | An NAD-dependent protein lipoamidase sirtuin-4, mitochondrial that is encoded in the genome of human. |
| Short Label | hSIRT4 |
| Category | organism-gene |
DAG ViewQ9Y6E7 (SIRT4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K13 | Acetylation | score1 | PhosphoSitePlus | |||
| K26 | Acetylation | score1 | PhosphoSitePlus | |||
| K43 | Acetylation | score1 | PhosphoSitePlus | |||
| K78 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S255 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
| S261 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
| S262 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17924679 | ||
| K299 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S261 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
