iPTMnet Report for Q9Y657 (SPIN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y657 / SPIN1_HUMAN
Protein Name Spindlin-1
Gene Name Name: SPIN1
Synonyms:OCR,SPIN;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y657
DAG View
PRO Name spindlin-1 (human)
Definition A spindlin-1 that is encoded in the genome of human.
Short Label hSPIN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y657 (SPIN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Methylation PhosphoSitePlus
T3 Phosphorylation PhosphoSitePlus
K7 Acetylation PhosphoSitePlus
K7 Methylation PhosphoSitePlus
S13 Phosphorylation HPRD 20068231
K28 Acetylation PhosphoSitePlus
S38 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 20068231
S39 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 20068231
S43 Phosphorylation HPRD   PhosphoSitePlus 20068231
K44 Ubiquitination PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
Y98 Phosphorylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
S109 Phosphorylation O14965 (AURKA) PhosphoSitePlus   Signor   UniProt 22258766
T120 Phosphorylation PhosphoSitePlus
S121 Phosphorylation HPRD 20068231
S124 Phosphorylation O14965 (AURKA) HPRD   phospho.ELM   PhosphoSitePlus   Signor   UniProt 23186163, 19651622, 18669648, ...22258766, 20068231
T131 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S196 Phosphorylation HPRD 20068231
S199 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
K216 Ubiquitination PhosphoSitePlus
K222 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 T2 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S39 I39 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S39 N39 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K104 N104 Biomuta DOID:3571 / liver cancer [ cosmic ]
S109 T109 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S109 Y109 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K222 E222 Biomuta DOID:10534 / stomach cancer [ cosmic ]