iPTMnet Report for Q9Y5Y9 (SCN10A)
Protein Information
UniProt AC / UniProt ID | Q9Y5Y9 / SCNAA_HUMAN |
Protein Name | Sodium channel protein type 10 subunit alpha |
Gene Name | Name: SCN10A |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y5Y9 |
PRO Name | sodium channel protein type 10 subunit alpha (human) |
Definition | A sodium channel protein type 10 subunit alpha that is encoded in the genome of human. |
Short Label | hSCN10A |
Category | organism-gene |
Q9Y5Y9 (SCN10A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T91 | Phosphorylation | score1 | PhosphoSitePlus | |||
T100 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
S552 | Phosphorylation | Q16539 (MAPK14) | score2 | neXtProt | 18354022 | |
Y723 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y724 | Phosphorylation | score1 | PhosphoSitePlus | |||
S930 | Phosphorylation | score1 | PhosphoSitePlus | |||
S933 | Phosphorylation | score1 | PhosphoSitePlus | |||
K957 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1188 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1208 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1441 | Acetylation | score1 | PhosphoSitePlus | |||
S1451 | Phosphorylation | Q02156 (PRKCE) | score2 | neXtProt | 22426212 | |
T1497 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1838 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1839 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1862 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1925 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1929 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T100 | I100 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S488 | F488 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S930 | G930 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y1208 | C1208 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
S1451 | F1451 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S1838 | F1838 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |