iPTMnet Report for Q9Y5X3 (SNX5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y5X3 / SNX5_HUMAN
Protein Name Sorting nexin-5
Gene Name Name: SNX5
Organism Homo sapiens (Human)

PRO ID PR:Q9Y5X3
DAG View
PRO Name sorting nexin-5 (human)
Definition A sorting nexin-5 that is encoded in the genome of human.
Short Label hSNX5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y5X3 (SNX5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
S20 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
K180 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus   UniProt 23186163
K203 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
S226 O-Glycosylation GlyGen 23301498, 30379171, 35008409
S226 Phosphorylation PhosphoSitePlus   RLIMS-P 30419003
K268 Ubiquitination PhosphoSitePlus
K275 Acetylation PhosphoSitePlus   UniProt 19608861
K275 Ubiquitination PhosphoSitePlus
R277 Methylation PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
Y310 Phosphorylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K337 Acetylation PhosphoSitePlus
K337 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K358 Ubiquitination PhosphoSitePlus
K365 Acetylation PhosphoSitePlus
K365 Methylation PhosphoSitePlus
K365 Ubiquitination PhosphoSitePlus
K367 Methylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S151 Phosphorylation HPRD 20068231
S152 Phosphorylation HPRD 20068231
S157 Phosphorylation HPRD 20068231
Y298 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S60 I60 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S151 F151 Biomuta DOID:4159 / skin cancer [ cosmic ]
T179 S179 Biomuta DOID:3571 / liver cancer [ cosmic ]
K203 Q203 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
K213 N213 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S226 Y226 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y298 S298 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y310 H310 Biomuta DOID:4159 / skin cancer [ cosmic ]