iPTMnet Report for Q9Y5S9 (RBM8A)
Protein Information
UniProt AC / UniProt ID | Q9Y5S9 / RBM8A_HUMAN |
Protein Name | RNA-binding protein 8A |
Gene Name | Name: RBM8A Synonyms:RBM8;ORFNames:HSPC114,MDS014; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y5S9 |
PRO Name | RNA-binding protein 8A (human) |
Definition | An RNA-binding protein 8A that is encoded in the genome of human. |
Short Label | hRBM8A |
Category | organism-gene |
Q9Y5S9 (RBM8A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 21406692, 20068231 | ||
S24 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 20068231 | ||
K27 | Acetylation | score1 | PhosphoSitePlus | |||
K27 | Sumoylation | score1 | PhosphoSitePlus | |||
R38 | Methylation | score1 | PhosphoSitePlus | |||
S42 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 16083285, 23186163, ... | ||
S46 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
Y54 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S56 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
K100 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y116 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y121 | Phosphorylation | score1 | PhosphoSitePlus | |||
T123 | Phosphorylation | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
S166 | Phosphorylation | Q96SB4 (SRPK1) | score4 | phospho.ELM PhosphoSitePlus RLIMS-P Signor | 25349214, 16100109, 17081983 | |
S168 | Phosphorylation | Q96SB4 (SRPK1) | score4 | phospho.ELM PhosphoSitePlus Signor | 16100109, 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S24 | Phosphorylation | score0 | HPRD | 20068231 | ||
S42 | Phosphorylation | score0 | HPRD | 16083285, 16964243, 19651622, ... | ||
S46 | Phosphorylation | score0 | HPRD | 15302935, 20068231 | ||
Y54 | Phosphorylation | score0 | HPRD | 18669648 | ||
S56 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
S166 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S168 | Phosphorylation | score0 | HPRD | 17081983, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R38 | Methylation | score1 | PhosphoSitePlus | |||
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S55 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | E2 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
A2 | V2 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
R38 | S38 | Biomuta | DOID:1324 / lung cancer [ cosmic, cosmic, icgc ] | |
Y121 | H121 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |