iPTMnet Report for Q9Y4P8 (WIPI2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4P8 / WIPI2_HUMAN
Protein Name WD repeat domain phosphoinositide-interacting protein 2
Gene Name Name: WIPI2
ORFNames:CGI-50;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4P8
DAG View
PRO Name WD repeat domain phosphoinositide-interacting protein 2 (human)
Definition A WD repeat domain phosphoinositide-interacting protein 2 that is encoded in the genome of human.
Short Label hWIPI2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4P8 (WIPI2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K28 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
K223 Acetylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
T292 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
S413 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T415 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Site PTM Type PTM Enzyme Score Source PMID
S413 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19664994, 19413330
T415 Phosphorylation HPRD 18669648, 19664994
Site PTM Type PTM Enzyme Score Source PMID
S395 Phosphorylation HPRD 17322306, 18767875, 18669648, ...19664994, 19413330
T397 Phosphorylation HPRD 18669648, 19664994
Site PTM Type PTM Enzyme Score Source PMID
T21 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K223 T223 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K341 N341 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
K371 T371 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T397 A397 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T397 M397 Biomuta DOID:363 / uterine cancer [ cosmic ]
S412 L412 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T415 A415 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T415 M415 Biomuta DOID:363 / uterine cancer [ cosmic ]