iPTMnet Report for Q9Y4P3 (TBL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4P3 / TBL2_HUMAN
Protein Name Transducin beta-like protein 2
Gene Name Name: TBL2
Synonyms:WBSCR13;ORFNames:UNQ563/PRO1125;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4P3
DAG View
PRO Name transducin beta-like protein 2 (human)
Definition A transducin beta-like protein 2 that is encoded in the genome of human.
Short Label hTBL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4P3 (TBL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S55 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S99 Phosphorylation PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
Y104 Phosphorylation HPRD 20068231
R112 Methylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S238 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K304 Ubiquitination PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
K314 Acetylation PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K315 Acetylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K322 Ubiquitination PhosphoSitePlus
T323 Phosphorylation PhosphoSitePlus
C335 Methylation IEDB 31844290
S340 Phosphorylation PhosphoSitePlus
K364 Acetylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
R394 Methylation PhosphoSitePlus
T402 Phosphorylation PhosphoSitePlus
K417 Methylation PhosphoSitePlus
K417 Ubiquitination PhosphoSitePlus
T433 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332
K440 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S55 Y55 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K71 M71 Biomuta DOID:263 / kidney cancer [ cosmic ]
S99 I99 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K103 T103 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R112 H112 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
K188 Q188 Biomuta DOID:1324 / lung cancer [ cosmic ]
K263 N263 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K364 E364 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
R394 W394 Biomuta DOID:1324 / lung cancer [ cosmic ]
R394 L394 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R394 G394 Biomuta DOID:1324 / lung cancer [ cosmic ]
T433 A433 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K440 N440 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]