iPTMnet Report for Q9Y4D7 (PLXND1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y4D7 / PLXD1_HUMAN
Protein Name Plexin-D1 precursor
Gene Name Name: PLXND1
Synonyms:KIAA0620;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y4D7
DAG View
PRO Name plexin-D1 (human)
Definition A plexin-D1 that is encoded in the genome of human.
Short Label hPLXND1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y4D7 (PLXND1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N123 N-Glycosylation GlyGen 24190977
N155 N-Glycosylation GlyGen 24190977
K332 Ubiquitination PhosphoSitePlus
N500 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 24190977, ...19159218, 29741879
N583 N-Glycosylation GlyGen 24190977
Y616 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
N696 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S838 Phosphorylation PhosphoSitePlus
S1075 Phosphorylation PhosphoSitePlus
S1079 Phosphorylation PhosphoSitePlus
T1086 Phosphorylation PhosphoSitePlus
T1088 Phosphorylation PhosphoSitePlus
K1324 Acetylation PhosphoSitePlus
K1324 Ubiquitination PhosphoSitePlus
K1338 Ubiquitination PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
K1362 Ubiquitination PhosphoSitePlus
Y1367 Phosphorylation PhosphoSitePlus
K1477 Ubiquitination PhosphoSitePlus
S1488 Phosphorylation PhosphoSitePlus
K1536 Acetylation PhosphoSitePlus
K1536 Ubiquitination PhosphoSitePlus
K1586 Ubiquitination PhosphoSitePlus
Y1642 Phosphorylation PhosphoSitePlus
S1649 Phosphorylation PhosphoSitePlus
K1657 Ubiquitination PhosphoSitePlus
K1658 Ubiquitination PhosphoSitePlus
T1661 Phosphorylation PhosphoSitePlus
K1672 Ubiquitination PhosphoSitePlus
Y1673 Phosphorylation PhosphoSitePlus
S1693 Phosphorylation PhosphoSitePlus
K1711 Ubiquitination PhosphoSitePlus
K1750 Ubiquitination PhosphoSitePlus
K1821 Ubiquitination PhosphoSitePlus
K1826 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T1534 Phosphorylation HPRD 20068231
T1661 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N123 T123 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1075 N1075 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1079 I1079 Biomuta DOID:363 / uterine cancer [ icgc ]
K1338 R1338 Biomuta DOID:363 / uterine cancer [ icgc ]
K1362 N1362 Biomuta DOID:363 / uterine cancer [ icgc ]
K1477 N1477 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1534 R1534 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K1586 M1586 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1642 C1642 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1649 F1649 Biomuta DOID:1319 / brain cancer [ cosmic ]
K1711 N1711 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1750 N1750 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
K1826 R1826 Biomuta DOID:1324 / lung cancer [ cosmic ]