iPTMnet Report for Q9Y487 (ATP6V0A2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y487 / VPP2_HUMAN
Protein Name V-type proton ATPase 116 kDa subunit a 2
Gene Name Name: ATP6V0A2
Organism Homo sapiens (Human)

PRO ID PR:Q9Y487
DAG View
PRO Name V-type proton ATPase 116 kDa subunit a 2 (human)
Definition A V-type proton ATPase 116 kDa subunit a 2 that is encoded in the genome of human.
Short Label hATP6V0A2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y487 (ATP6V0A2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K92 Ubiquitination PhosphoSitePlus
K115 Acetylation PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
Y163 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S177 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
Y223 Phosphorylation PhosphoSitePlus
K279 Acetylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
C323 Methylation IEDB 31844290
S349 Phosphorylation HPRD   PhosphoSitePlus 18452278
T352 Phosphorylation HPRD   PhosphoSitePlus 18452278
S355 Phosphorylation HPRD   PhosphoSitePlus 18452278
K363 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
N477 N-Glycosylation GlyGen 24190977
N484 N-Glycosylation GlyGen 24190977
S490 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus
S492 Phosphorylation PhosphoSitePlus
N505 N-Glycosylation GlyGen 29741879, 24190977
S507 Phosphorylation PhosphoSitePlus
Y688 Phosphorylation PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
S695 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18669648, ...17081983
S700 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S704 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S154 F154 Biomuta DOID:4159 / skin cancer [ cosmic ]
S177 F177 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y223 C223 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S355 L355 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K363 R363 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S490 N490 Biomuta DOID:363 / uterine cancer [ icgc ]
S507 R507 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]