iPTMnet Report for Q9Y3P8 (SIT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y3P8 / SIT1_HUMAN
Protein Name Signaling threshold-regulating transmembrane adapter 1 precursor
Gene Name Name: SIT1
Synonyms:SIT;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y3P8
DAG View
PRO Name signaling threshold-regulating transmembrane adapter 1 (human)
Definition A signaling threshold-regulating transmembrane adapter 1 that is encoded in the genome of human.
Short Label hSIT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y3P8 (SIT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N26 N-Glycosylation GlyGen   UniProt 10209036
S73 Phosphorylation PhosphoSitePlus
S80 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15144186
S83 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15570572, 16094384
Y90 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 15592455, 15144186, 11433379
Y95 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455, 15144186
T98 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 16094384
S102 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19690332, 16094384
Y127 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 10209036, 11433379
T128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
T144 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19690332, 15144186
K147 Ubiquitination PhosphoSitePlus
Y148 Phosphorylation HPRD   IntAct   phospho.ELM   PhosphoSitePlus   UniProt 15659558, 10209036, 16094384, ...15144186, 11433379, 19690332
S149 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15144186
S162 Phosphorylation PhosphoSitePlus
Y169 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 10209036, 11433379
S171 O-Glycosylation GlyGen 35132862
S171 Phosphorylation PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
S182 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 33936100, 15144186, 19690332
Y188 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 10209036, 15144186, 11433379, ...15592455, 19690332
S191 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N26 K26 Biomuta DOID:3571 / liver cancer [ cosmic ]