iPTMnet Report for Q9Y385 (UBE2J1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y385 / UB2J1_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 J1
Gene Name Name: UBE2J1
Synonyms:NCUBE1;ORFNames:CGI-76,HSPC153,HSPC205;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y385
DAG View
PRO Name ubiquitin-conjugating enzyme E2 J1 (human)
Definition A ubiquitin-conjugating enzyme E2 J1 that is encoded in the genome of human.
Short Label hUBE2J1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y385 (UBE2J1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y5 Phosphorylation PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
C91 Methylation IEDB 31844290
K143 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
S184 Phosphorylation P49137 (MAPKAPK2) IEDB   PhosphoSitePlus   RLIMS-P+   RLIMS-P   Signor   UniProt 23186163, 16720581, 24020373, ...28321712, 30784271, 32387766
K186 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
S197 Phosphorylation IEDB 29437277
S251 O-Glycosylation GlyGen 30620550
S251 Phosphorylation PhosphoSitePlus
S266 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18578522, 23186163, 17081983, ...18767875, 20058876, 21406692, 19651622, 18669648, 24275569, 20166139, 20068231, 17924679
T267 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983, 20058876, 19651622, ...18669648, 20166139
S268 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18578522, 23186163, 17081983, ...18669648, 17924679
T282 Phosphorylation PhosphoSitePlus
T295 Phosphorylation PhosphoSitePlus
Y312 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S184 R184 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ icgc ] DOID:1115 / sarcoma [ icgc ]
K194 N194 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S251 R251 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T267 I267 Biomuta DOID:4159 / skin cancer [ cosmic ]