iPTMnet Report for Q9Y2N7 (HIF3A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9Y2N7 / HIF3A_HUMAN
Protein Name Hypoxia-inducible factor 3-alpha
Gene Name Name: HIF3A
Synonyms:BHLHE17,MOP7,PASD7;
Organism Homo sapiens (Human)

PRO ID PR:Q9Y2N7
DAG View
PRO Name hypoxia-inducible factor 3-alpha (human)
Definition A hypoxia-inducible factor 3-alpha that is encoded in the genome of human.
Short Label hHIF3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9Y2N7 (HIF3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation Q9BXM7 (PINK1) RLIMS-P+   Signor 27551449
S28 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
S396 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus   UniProt 12538644
K570 Ubiquitination PhosphoSitePlus   UniProt 12538644


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 N28 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y35 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T173 I173 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S396 F396 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S398 N398 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]