iPTMnet Report for Q9Y2L9 (LRCH1)
Protein Information
| UniProt AC / UniProt ID | Q9Y2L9 / LRCH1_HUMAN |
| Protein Name | Leucine-rich repeat and calponin homology domain-containing protein 1 |
| Gene Name | Name: LRCH1 Synonyms:CHDC1,KIAA1016; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9Y2L9 |
| PRO Name | leucine-rich repeat and calponin homology domain-containing protein 1 (human) |
| Definition | A leucine-rich repeat and calponin homology domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hLRCH1 |
| Category | organism-gene |
DAG ViewQ9Y2L9 (LRCH1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C242 | Methylation | score1 | IEDB | 31844290 | ||
| C251 | Methylation | score1 | IEDB | 31844290 | ||
| S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S370 | Phosphorylation | score2 | IEDB PhosphoSitePlus UniProt | 27920218, 32387766, 27869121, ... | ||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S532 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S536 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T538 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S551 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T568 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S623 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S626 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T391 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S532 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S536 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S562 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T568 | Phosphorylation | score0 | HPRD | 18669648, 19664994, 20068231 |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K662 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K673 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C242 | S242 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S340 | F340 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S346 | G346 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| S346 | N346 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| S365 | L365 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S370 | I370 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S532 | F532 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S532 | C532 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
