iPTMnet Report for Q9Y2L9 (LRCH1)
Protein Information
UniProt AC / UniProt ID | Q9Y2L9 / LRCH1_HUMAN |
Protein Name | Leucine-rich repeat and calponin homology domain-containing protein 1 |
Gene Name | Name: LRCH1 Synonyms:CHDC1,KIAA1016; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y2L9 |
PRO Name | leucine-rich repeat and calponin homology domain-containing protein 1 (human) |
Definition | A leucine-rich repeat and calponin homology domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hLRCH1 |
Category | organism-gene |
Q9Y2L9 (LRCH1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
C242 | Methylation | score1 | IEDB | 31844290 | ||
C251 | Methylation | score1 | IEDB | 31844290 | ||
S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
S346 | Phosphorylation | score1 | PhosphoSitePlus | |||
S365 | Phosphorylation | score1 | PhosphoSitePlus | |||
S370 | Phosphorylation | score2 | IEDB PhosphoSitePlus UniProt | 27920218, 32387766, 27869121, ... | ||
S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
K415 | Ubiquitination | score1 | PhosphoSitePlus | |||
S532 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S536 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T538 | Phosphorylation | score1 | PhosphoSitePlus | |||
S551 | Phosphorylation | score1 | PhosphoSitePlus | |||
S562 | Phosphorylation | score1 | PhosphoSitePlus | |||
T568 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S623 | Phosphorylation | score1 | PhosphoSitePlus | |||
S626 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T391 | Phosphorylation | score0 | HPRD | 20068231 | ||
S532 | Phosphorylation | score0 | HPRD | 20068231 | ||
S536 | Phosphorylation | score0 | HPRD | 20068231 | ||
S562 | Phosphorylation | score0 | HPRD | 20068231 | ||
T568 | Phosphorylation | score0 | HPRD | 18669648, 19664994, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K662 | Ubiquitination | score1 | PhosphoSitePlus | |||
K673 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C242 | S242 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S340 | F340 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S346 | G346 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S346 | N346 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S365 | L365 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S370 | I370 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
S532 | F532 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S532 | C532 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |