iPTMnet Report for Q9Y277 (VDAC3)
Protein Information
UniProt AC / UniProt ID | Q9Y277 / VDAC3_HUMAN |
Protein Name | Voltage-dependent anion-selective channel protein 3 |
Gene Name | Name: VDAC3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9Y277 |
PRO Name | voltage-dependent anion-selective channel protein 3 (human) |
Definition | A voltage-dependent anion-selective channel protein 3 that is encoded in the genome of human. |
Short Label | hVDAC3 |
Category | organism-gene |
Q9Y277 (VDAC3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Ubiquitination | score1 | PRO | ||||
C2 | Acetylation | score1 | UniProt | 19413330, 25944712 | ||
T4 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T6 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y7 | Phosphorylation | score1 | PhosphoSitePlus | |||
K12 | Acetylation | score1 | PhosphoSitePlus | |||
K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
K15 | Acetylation | score1 | PhosphoSitePlus | |||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
K20 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y22 | Phosphorylation | score1 | PhosphoSitePlus | |||
K28 | Acetylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
C36 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y48 | Phosphorylation | score1 | PhosphoSitePlus | |||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K61 | Acetylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K63 | Acetylation | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
C65 | S-Nitrosylation | score0 | dbSNO | 20140087 | ||
Y67 | Phosphorylation | score1 | PhosphoSitePlus | |||
T70 | O-Glycosylation | score1 | GlyGen | 23301498, 27655845, 34725712, ... | ||
T70 | Phosphorylation | score1 | PhosphoSitePlus | |||
K90 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K90 | Ubiquitination | score1 | PhosphoSitePlus | |||
K96 | Acetylation | score1 | PhosphoSitePlus | |||
T107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K109 | Acetylation | score1 | PhosphoSitePlus | |||
K109 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K110 | Acetylation | score1 | PhosphoSitePlus | |||
K110 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K113 | Acetylation | score1 | PhosphoSitePlus | |||
K115 | Acetylation | score1 | PhosphoSitePlus | |||
K119 | Acetylation | score1 | PhosphoSitePlus | |||
K163 | Acetylation | score1 | PhosphoSitePlus | |||
K163 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
K174 | Acetylation | score1 | PhosphoSitePlus | |||
Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Acetylation | score1 | PhosphoSitePlus | |||
C229 | Methylation | score1 | IEDB | 31844290 | ||
Y247 | Phosphorylation | score1 | PhosphoSitePlus | |||
T248 | Phosphorylation | score1 | PhosphoSitePlus | |||
T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
S260 | Phosphorylation | score1 | PhosphoSitePlus | |||
K266 | Acetylation | score1 | PhosphoSitePlus | |||
K266 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K274 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S43 | Phosphorylation | score1 | PhosphoSitePlus | |||
T44 | Phosphorylation | score1 | PhosphoSitePlus | |||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y49 | Phosphorylation | score1 | PhosphoSitePlus | |||
T50 | Phosphorylation | score1 | PhosphoSitePlus | |||
T52 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000049654 (hVDAC3/InitMet-/UbiqLys+) | ub | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S44 | F44 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T44 | I44 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S45 | F45 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T70 | S70 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K109 | N109 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
K110 | N110 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K224 | E224 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K224 | Q224 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y247 | H247 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K274 | E274 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |