iPTMnet Report for Q9UPT6 (MAPK8IP3)
Protein Information
UniProt AC / UniProt ID | Q9UPT6 / JIP3_HUMAN |
Protein Name | C-Jun-amino-terminal kinase-interacting protein 3 |
Gene Name | Name: MAPK8IP3 Synonyms:JIP3,KIAA1066; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UPT6 |
PRO Name | C-Jun-amino-terminal kinase-interacting protein 3 (human) |
Definition | A C-Jun-amino-terminal kinase-interacting protein 3 that is encoded in the genome of human. |
Short Label | hMAPK8IP3 |
Category | organism-gene |
Q9UPT6 (MAPK8IP3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R84 | Methylation | score1 | PhosphoSitePlus | |||
R101 | Methylation | score1 | PhosphoSitePlus | |||
R102 | Methylation | score1 | PhosphoSitePlus | |||
K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
K139 | Sumoylation | score1 | PhosphoSitePlus | |||
S148 | Phosphorylation | score1 | PhosphoSitePlus | |||
K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
K183 | Ubiquitination | score1 | PhosphoSitePlus | |||
T206 | Phosphorylation | score1 | PhosphoSitePlus | |||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T265 | Phosphorylation | score4 | neXtProt Signor | 15767678, 10523642 | ||
T265 | Phosphorylation | P45983 (MAPK8) | score4 | neXtProt Signor | 10523642, 15767678 | |
T265 | Phosphorylation | P45984 (MAPK9) | score4 | neXtProt Signor | 15767678, 10523642 | |
T265 | Phosphorylation | P53779 (MAPK10) | score4 | neXtProt Signor | 10523642, 15767678 | |
T275 | Phosphorylation | score4 | neXtProt Signor | 15767678, 10523642 | ||
T275 | Phosphorylation | P45983 (MAPK8) | score4 | neXtProt Signor | 10523642, 15767678 | |
T275 | Phosphorylation | P45984 (MAPK9) | score4 | neXtProt Signor | 15767678, 10523642 | |
T275 | Phosphorylation | P53779 (MAPK10) | score4 | neXtProt Signor | 15767678, 10523642 | |
T286 | Phosphorylation | score4 | neXtProt Signor | 15767678, 10523642 | ||
T286 | Phosphorylation | P45983 (MAPK8) | score4 | neXtProt Signor | 15767678, 10523642 | |
T286 | Phosphorylation | P45984 (MAPK9) | score4 | neXtProt Signor | 15767678, 10523642 | |
T286 | Phosphorylation | P53779 (MAPK10) | score4 | neXtProt Signor | 10523642, 15767678 | |
S314 | Phosphorylation | score4 | PhosphoSitePlus Signor UniProt | 15767678, 19036714 | ||
S314 | Phosphorylation | Q13464 (ROCK1) | score4 | PhosphoSitePlus Signor | 15767678, 19036714 | |
T362 | Phosphorylation | score1 | PhosphoSitePlus | |||
S364 | Phosphorylation | score4 | PhosphoSitePlus Signor UniProt | 15767678, 19036714 | ||
S364 | Phosphorylation | Q13464 (ROCK1) | score4 | PhosphoSitePlus Signor | 15767678, 19036714 | |
S365 | Phosphorylation | score4 | PhosphoSitePlus Signor UniProt | 15767678, 19036714 | ||
S365 | Phosphorylation | Q13464 (ROCK1) | score4 | PhosphoSitePlus Signor | 15767678, 19036714 | |
S563 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
S584 | Phosphorylation | score1 | PhosphoSitePlus | |||
S585 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935 | ||
S602 | Phosphorylation | score1 | PhosphoSitePlus | |||
T605 | Phosphorylation | score1 | PhosphoSitePlus | |||
S676 | Phosphorylation | score1 | PhosphoSitePlus | |||
T684 | Phosphorylation | score1 | PhosphoSitePlus | |||
S716 | Phosphorylation | score1 | PhosphoSitePlus | |||
T779 | Phosphorylation | score1 | PhosphoSitePlus | |||
S863 | Phosphorylation | score1 | PhosphoSitePlus | |||
S864 | Phosphorylation | score1 | PhosphoSitePlus | |||
T913 | Phosphorylation | score1 | PhosphoSitePlus | |||
K997 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1004 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1143 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S1191 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1260 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1286 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T265 | Phosphorylation | score2 | HPRD | 10523642, 10629060 | ||
T265 | Phosphorylation | P45983 (MAPK8) | score1 | HPRD | 10629060 | |
T265 | Phosphorylation | P53779 (MAPK10) | score1 | HPRD | 10523642 | |
T275 | Phosphorylation | score2 | HPRD | 10523642, 10629060 | ||
T275 | Phosphorylation | P45983 (MAPK8) | score1 | HPRD | 10629060 | |
T275 | Phosphorylation | P53779 (MAPK10) | score1 | HPRD | 10523642 | |
T286 | Phosphorylation | score2 | HPRD | 10523642, 10629060 | ||
T286 | Phosphorylation | P45983 (MAPK8) | score1 | HPRD | 10629060 | |
T286 | Phosphorylation | P53779 (MAPK10) | score1 | HPRD | 10523642 | |
S585 | Phosphorylation | score0 | HPRD | 15302935 | ||
S676 | Phosphorylation | score0 | HPRD | 20068231 | ||
T684 | Phosphorylation | score0 | HPRD | 20068231 | ||
S716 | Phosphorylation | score0 | HPRD | 20068231 | ||
T913 | Phosphorylation | score0 | HPRD | 20068231 | ||
S1143 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R101 | C101 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T275 | M275 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S314 | I314 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S563 | F563 | Biomuta | [ cosmic ] | |
S1143 | F1143 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |