iPTMnet Report for Q9UPN4 (CEP131)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UPN4 / CP131_HUMAN
Protein Name Centrosomal protein of 131 kDa
Gene Name Name: CEP131
Synonyms:AZI1,KIAA1118;
Organism Homo sapiens (Human)

PRO ID PR:Q9UPN4
DAG View
PRO Name centrosomal protein of 131 kDa (human)
Definition A centrosomal protein of 131 kDa that is encoded in the genome of human.
Short Label hCEP131
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UPN4 (CEP131) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S14 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23186163, 30266825
K40 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S47 Phosphorylation P49137 (MAPKAPK2) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 26616734, ...18669648, 29932434, 19690332
S52 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S76 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S78 Phosphorylation P49137 (MAPKAPK2) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 29932434, 30804208, ...26616734, 18669648
T79 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T80 Phosphorylation PhosphoSitePlus
S87 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S89 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T93 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T96 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S105 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 19690332
S107 Phosphorylation phospho.ELM 18669648
K110 Ubiquitination PhosphoSitePlus
S114 Phosphorylation PhosphoSitePlus   UniProt 23186163
S116 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus   UniProt 23186163
S150 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 16964243
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K200 Methylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
T205 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
K214 Methylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K231 Ubiquitination PhosphoSitePlus
T244 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
K320 Ubiquitination PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S381 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
T383 Phosphorylation PhosphoSitePlus   UniProt 23186163
K393 Ubiquitination PhosphoSitePlus
T413 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus   UniProt 21406692
S489 Phosphorylation UniProt 19369195, 19690332
D496 Phosphorylation UniProt 19690332
S499 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
S534 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
S613 Phosphorylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K656 Ubiquitination PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
K681 Ubiquitination PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
S697 Phosphorylation PhosphoSitePlus
K699 Ubiquitination PhosphoSitePlus
K704 Ubiquitination PhosphoSitePlus
T707 Phosphorylation PhosphoSitePlus
K717 Ubiquitination PhosphoSitePlus
K730 Methylation PhosphoSitePlus
K730 Ubiquitination PhosphoSitePlus
S731 Phosphorylation IEDB   PhosphoSitePlus   RLIMS-P   UniProt 35494241, 26616734
S745 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
Y797 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus   UniProt 23186163, 19690332
T857 Phosphorylation PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
K876 Ubiquitination PhosphoSitePlus
K932 Ubiquitination PhosphoSitePlus
K955 Ubiquitination PhosphoSitePlus
S990 Phosphorylation PhosphoSitePlus
S991 Phosphorylation PhosphoSitePlus
S994 Phosphorylation PhosphoSitePlus
R1007 Methylation PhosphoSitePlus
K1019 Ubiquitination PhosphoSitePlus
T1024 Phosphorylation PhosphoSitePlus
T1079 Phosphorylation PhosphoSitePlus
T1082 O-Glycosylation GlyGen 35254053
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation HPRD 18669648
S52 Phosphorylation HPRD 19007248
S76 Phosphorylation HPRD 18669648, 19664995
S78 Phosphorylation HPRD   PhosphoSitePlus 18669648
T79 Phosphorylation HPRD   PhosphoSitePlus 18669648
S87 Phosphorylation HPRD 19651622, 18669648, 20068231
S89 Phosphorylation HPRD   PhosphoSitePlus 18669648
T93 Phosphorylation HPRD 18669648, 20068231
T96 Phosphorylation HPRD 18669648, 20068231, 18452278
S105 Phosphorylation HPRD 18669648, 20068231, 18452278
S107 Phosphorylation HPRD 18669648
S150 Phosphorylation HPRD 19664995, 16964243, 19664994, ...19007248, 19691289, 18669648
S381 Phosphorylation HPRD 20068231
S489 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S496 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
S728 Phosphorylation HPRD 19413330
S742 Phosphorylation HPRD 17525332
Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation HPRD 18669648
S52 Phosphorylation HPRD 19007248
S76 Phosphorylation HPRD 18669648, 19664995
S78 Phosphorylation HPRD 18669648
T79 Phosphorylation HPRD 18669648
S87 Phosphorylation HPRD 19651622, 18669648, 20068231
S89 Phosphorylation HPRD 18669648
T93 Phosphorylation HPRD 18669648, 20068231
T96 Phosphorylation HPRD 18669648, 20068231, 18452278
S105 Phosphorylation HPRD 18669648, 20068231, 18452278
S107 Phosphorylation HPRD 18669648
S150 Phosphorylation HPRD 19664995, 16964243, 19664994, ...19007248, 19691289, 18669648
S381 Phosphorylation HPRD 20068231
S728 Phosphorylation HPRD 19413330
S742 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S52 N52 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T80 M80 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S107 T107 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S107 R107 Biomuta DOID:1612 / breast cancer [ cosmic ]
S145 F145 Biomuta DOID:4159 / skin cancer [ cosmic ]
S208 F208 Biomuta DOID:4159 / skin cancer [ cosmic ]
S221 C221 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T244 I244 Biomuta [ cosmic ]
T257 M257 Biomuta DOID:3571 / liver cancer [ cosmic ]
K300 R300 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S381 F381 Biomuta [ cosmic ]
S489 I489 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S489 N489 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K510 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T522 M522 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S525 L525 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K678 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K730 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S742 L742 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, cosmic ]
S745 L745 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K955 N955 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S990 F990 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
R1007 Q1007 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T1024 M1024 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1079 M1079 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]