iPTMnet Report for Q9UNX4 (WDR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UNX4 / WDR3_HUMAN
Protein Name WD repeat-containing protein 3
Gene Name Name: WDR3
Organism Homo sapiens (Human)

PRO ID PR:Q9UNX4
DAG View
PRO Name WD repeat-containing protein 3 (human)
Definition A WD repeat-containing protein 3 that is encoded in the genome of human.
Short Label hWDR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UNX4 (WDR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y10 Phosphorylation HPRD   PhosphoSitePlus 20068231
S13 Phosphorylation HPRD   PhosphoSitePlus 20068231
K57 Ubiquitination PhosphoSitePlus
S96 Phosphorylation HPRD 20068231
T102 Phosphorylation HPRD   PhosphoSitePlus 20068231
K114 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
C183 Methylation IEDB 31844290
S211 Phosphorylation PhosphoSitePlus
K235 Acetylation PhosphoSitePlus
K235 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
S240 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19664995, 16565220, 18669648, ...18452278, 20068231
S241 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19664995, 18452278, 19651622, ...18669648, 19415658, 20068231
T247 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17081983, 19664995, ...18452278, 18669648
T257 Phosphorylation PhosphoSitePlus   UniProt 23186163
K270 Ubiquitination PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus
S333 Phosphorylation HPRD   phospho.ELM 18669648
K360 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
K474 Ubiquitination PhosphoSitePlus
K518 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
K529 Sumoylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
K536 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
S586 Phosphorylation PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
S645 Phosphorylation PhosphoSitePlus
K653 Acetylation PhosphoSitePlus
K653 Ubiquitination PhosphoSitePlus
Y723 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus   UniProt 23186163
K729 Ubiquitination PhosphoSitePlus
S743 Phosphorylation HPRD 20068231
K748 Ubiquitination PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
K755 Ubiquitination PhosphoSitePlus
S792 O-Glycosylation GlyGen 34105348
S801 O-Glycosylation GlyGen 34105348
R854 Methylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
K906 Ubiquitination PhosphoSitePlus
T941 Phosphorylation HPRD   PhosphoSitePlus 20068231
T943 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T102 I102 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T257 M257 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y456 F456 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T580 N580 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S726 C726 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K748 M748 Biomuta DOID:1324 / lung cancer [ cosmic ]
R854 W854 Biomuta DOID:9256 / colorectal cancer [ cosmic ]