iPTMnet Report for Q9UMX0 (UBQLN1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UMX0 / UBQL1_HUMAN
Protein Name Ubiquilin-1
Gene Name Name: UBQLN1
Synonyms:DA41,PLIC1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UMX0
DAG View
PRO Name ubiquilin-1 (human)
Definition A ubiquilin-1 that is encoded in the genome of human.
Short Label hUBQLN1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UMX0 (UBQLN1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 21406692, 22223895, ...20068231
S4 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K62 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
R253 Methylation PhosphoSitePlus
R257 Methylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
R273 Methylation PhosphoSitePlus
T277 O-Glycosylation GlyGen 31373491
T277 Phosphorylation PhosphoSitePlus
S298 O-Glycosylation GlyGen 31373491
T328 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 29351928, 34019948, 28510447
S329 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 29351928, 34019948, 28510447
S335 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 29351928, 34019948, 28510447
T349 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 29351928, 34019948, 28510447
T518 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...35138101, 29351928, 34019948, 28510447
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation HPRD 19664995
S16 Phosphorylation HPRD 20068231
T43 Phosphorylation HPRD 20068231
Y269 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation HPRD 19664995
S16 Phosphorylation HPRD 20068231
T43 Phosphorylation HPRD 20068231
Y269 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K35 Q35 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K70 E70 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
R253 M253 Biomuta DOID:1324 / lung cancer [ cosmic ]
R257 Q257 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S260 I260 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S264 R264 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T349 A349 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]