iPTMnet Report for Q9UMS6 (SYNPO2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UMS6 / SYNP2_HUMAN
Protein Name Synaptopodin-2
Gene Name Name: SYNPO2
Organism Homo sapiens (Human)

PRO ID PR:Q9UMS6
DAG View
PRO Name synaptopodin-2 (human)
Definition A synaptopodin-2 that is encoded in the genome of human.
Short Label hSYNPO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UMS6 (SYNPO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y112 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
S243 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus   UniProt 24275569
S310 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S363 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S374 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
T408 Phosphorylation PhosphoSitePlus
T506 Phosphorylation PhosphoSitePlus
T517 Phosphorylation PhosphoSitePlus
S519 Phosphorylation PhosphoSitePlus
S548 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
T601 Phosphorylation PhosphoSitePlus
S604 Phosphorylation PhosphoSitePlus
T606 Phosphorylation PhosphoSitePlus
T610 Phosphorylation PhosphoSitePlus   UniProt 24275569
S611 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y622 Phosphorylation PhosphoSitePlus   UniProt 24275569
S623 Phosphorylation PhosphoSitePlus
T626 Phosphorylation PhosphoSitePlus   UniProt 24275569
S633 Phosphorylation PhosphoSitePlus
S638 Phosphorylation PhosphoSitePlus
S675 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
T692 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S717 Phosphorylation PhosphoSitePlus
K720 Acetylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus   UniProt 24275569
S737 Phosphorylation PhosphoSitePlus
T755 Phosphorylation PhosphoSitePlus   UniProt 24275569
K766 Acetylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
S770 Phosphorylation PhosphoSitePlus
T774 Phosphorylation PhosphoSitePlus   UniProt 24275569
S777 Phosphorylation PhosphoSitePlus   UniProt 24275569
S781 Phosphorylation PhosphoSitePlus
T787 Phosphorylation PhosphoSitePlus
S798 Phosphorylation PhosphoSitePlus
T801 Phosphorylation PhosphoSitePlus
Y813 Phosphorylation PhosphoSitePlus
S820 Phosphorylation PhosphoSitePlus
Y840 Phosphorylation PhosphoSitePlus
Y886 Phosphorylation PhosphoSitePlus
T892 Phosphorylation PhosphoSitePlus
S902 Phosphorylation PhosphoSitePlus   UniProt 24275569
T904 Phosphorylation PhosphoSitePlus
S906 Phosphorylation PhosphoSitePlus   UniProt 24275569
S910 Phosphorylation PhosphoSitePlus
Y925 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
S932 Phosphorylation PhosphoSitePlus
Y933 Phosphorylation PhosphoSitePlus
S998 Phosphorylation PhosphoSitePlus
S1041 Phosphorylation PhosphoSitePlus
S1042 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
T1055 Phosphorylation PhosphoSitePlus
S1056 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y1066 Phosphorylation PhosphoSitePlus
S1079 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T506 Phosphorylation HPRD 19651622
S519 Phosphorylation HPRD 19651622
S604 Phosphorylation HPRD 20166139
T606 Phosphorylation HPRD 20166139
S902 Phosphorylation HPRD 20166139
T904 Phosphorylation HPRD 20166139
S906 Phosphorylation HPRD 20166139
S1079 Phosphorylation PhosphoSitePlus
T1082 Phosphorylation PhosphoSitePlus
S1091 Phosphorylation PhosphoSitePlus
T1111 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation PhosphoSitePlus
S1138 Phosphorylation PhosphoSitePlus
S1155 Phosphorylation PhosphoSitePlus
S1181 Phosphorylation PhosphoSitePlus
Y1182 Phosphorylation PhosphoSitePlus
Y1199 Phosphorylation PhosphoSitePlus
Y1222 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation PhosphoSitePlus
S1230 Phosphorylation PhosphoSitePlus
S1239 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S202 C202 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S202 P202 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S224 F224 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S226 Y226 Biomuta DOID:363 / uterine cancer [ icgc ]
S243 W243 Biomuta DOID:1612 / breast cancer [ icgc ]
S243 L243 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S256 Y256 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S263 Y263 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S274 I274 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S310 F310 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
S310 C310 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S361 R361 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S361 I361 Biomuta DOID:3571 / liver cancer [ cosmic ]
S363 R363 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S363 I363 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S365 L365 Biomuta DOID:1324 / lung cancer [ cosmic ]
S374 Y374 Biomuta DOID:363 / uterine cancer [ icgc ]
S374 P374 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K398 N398 Biomuta DOID:363 / uterine cancer [ icgc ]
T408 I408 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T517 M517 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
S519 R519 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S519 C519 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T601 S601 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T610 M610 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S611 R611 Biomuta DOID:1324 / lung cancer [ cosmic ]
S675 L675 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S691 N691 Biomuta DOID:3571 / liver cancer [ cosmic ]
T692 M692 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
T755 I755 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S777 F777 Biomuta DOID:4159 / skin cancer [ cosmic ]
S798 * Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]
T801 I801 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y813 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y813 H813 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T904 S904 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S910 R910 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S930 L930 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1042 L1042 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1047 F1047 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1055 S1055 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1056 L1056 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1091 F1091 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1155 F1155 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y1199 C1199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1239 C1239 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc, cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]