iPTMnet Report for Q9UM00 (TMCO1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UM00 / TMCO1_HUMAN
Protein Name Calcium load-activated calcium channel
Gene Name Name: TMCO1
Synonyms:TMCC4;ORFNames:PNAS-10,PNAS-136,UNQ151/PRO177;
Organism Homo sapiens (Human)

PRO ID PR:Q9UM00
DAG View
PRO Name calcium load-activated calcium channel (human)
Definition A calcium load-activated calcium channel that is encoded in the genome of human.
Short Label hTMCO1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UM00 (TMCO1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C35 Methylation IEDB 31844290
C68 Methylation IEDB 31844290
S111 Phosphorylation UniProt 18669648, 20068231
T171 O-Glycosylation GlyGen 34019948, 33465208
S174 O-Glycosylation GlyGen 33465208
S239 Phosphorylation UniProt 18691976, 18669648, 20068231
Site PTM Type PTM Enzyme Score Source PMID
K40 Ubiquitination PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
T120 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S111 L111 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S239 F239 Biomuta DOID:10283 / prostate cancer [ cosmic ]