iPTMnet Report for Q9ULM3 (YEATS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULM3 / YETS2_HUMAN
Protein Name YEATS domain-containing protein 2
Gene Name Name: YEATS2
Synonyms:KIAA1197;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULM3
DAG View
PRO Name YEATS domain-containing protein 2 (human)
Definition A YEATS domain-containing protein 2 that is encoded in the genome of human.
Short Label hYEATS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULM3 (YEATS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K57 Acetylation PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S118 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19664995, 20068231, ...19691289
S120 Phosphorylation HPRD   PhosphoSitePlus 20068231
S122 Phosphorylation HPRD 20068231
S123 Phosphorylation HPRD 20068231
S124 Phosphorylation PhosphoSitePlus
T132 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
S144 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S157 Phosphorylation PhosphoSitePlus   UniProt 23186163
T209 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
S367 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648
T379 Phosphorylation HPRD   PhosphoSitePlus 18452278
S380 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
S388 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T389 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T395 Phosphorylation PhosphoSitePlus
S402 Phosphorylation HPRD   PhosphoSitePlus 20068231
S403 Phosphorylation PhosphoSitePlus
T407 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T409 Phosphorylation HPRD   PhosphoSitePlus 20068231
C420 Methylation IEDB 31844290
S447 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...19664994, 15302935, 19664995, 19691289, 20068231
K450 Acetylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus
S463 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19664995, 20068231, ...19691289
S465 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 15302935, ...19691289, 18452278, 19664995, 20068231
S468 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S471 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
S473 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 23186163, 20068231, ...18452278
T478 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T478 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 19691289, 24275569
T480 Phosphorylation PhosphoSitePlus
S481 Phosphorylation PhosphoSitePlus
T482 Phosphorylation PhosphoSitePlus
T513 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 31637018, 30379171, 32574038, 32938750, 34019948, 21740066, 30059200, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092
T514 Phosphorylation HPRD   PhosphoSitePlus 20068231
S516 Phosphorylation HPRD 20068231
S519 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 15302935, 19664995, ...20068231
T521 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 18669648
S525 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S531 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S531 Phosphorylation HPRD   PhosphoSitePlus 18077418
T534 Phosphorylation PhosphoSitePlus
S536 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18077418, 19664994, 19651622, 19690332
K552 Sumoylation PhosphoSitePlus
S575 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T587 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
K592 Sumoylation PhosphoSitePlus
T604 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 31637018, 30379171, 32574038, 32938750, 34019948, 21740066, 30059200, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092
S608 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S610 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S610 Phosphorylation PhosphoSitePlus
T617 O-Glycosylation GlyGen 34846842
S627 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19691289, 20068231
T634 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K649 Ubiquitination PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
S670 O-Glycosylation GlyGen 34846842
K685 Ubiquitination PhosphoSitePlus
K690 Ubiquitination PhosphoSitePlus
S703 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 31637018, 30379171, 32574038, 32938750, 34019948, 21740066, 30059200, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092
T708 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T718 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
K719 Ubiquitination PhosphoSitePlus
T723 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S765 Phosphorylation HPRD   PhosphoSitePlus 18691976
K766 Ubiquitination PhosphoSitePlus
K773 Sumoylation PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
T878 O-Glycosylation GlyGen 32938750
S880 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T885 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S889 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S891 O-Glycosylation GlyGen 34846842
T898 O-Glycosylation GlyGen 34846842
S903 Phosphorylation HPRD   PhosphoSitePlus 19413330
T911 Phosphorylation HPRD   PhosphoSitePlus 19413330
K923 Ubiquitination PhosphoSitePlus
K930 Ubiquitination PhosphoSitePlus
K940 Ubiquitination PhosphoSitePlus
S964 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S972 O-Glycosylation GlyGen 32938750
T989 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 31637018, 30379171, 32574038, 32938750, 34019948, 21740066, 30059200, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092
S990 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S998 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 31637018, 30379171, 32574038, 32938750, 34019948, 21740066, 30059200, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092
T1011 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S1014 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T1016 O-Glycosylation GlyGen 21740066
S1017 O-Glycosylation GlyGen 21740066
T1021 Phosphorylation PhosphoSitePlus
S1039 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1040 Phosphorylation PhosphoSitePlus
S1043 Phosphorylation PhosphoSitePlus
S1059 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T1062 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
S1063 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 31637018, 30379171, 32574038, 34019948, 21740066, 35254053, 35132862, 30620550, 31492838, 20305658, 32119511, 35289036, 29351928, 28657654, 29237092, 30059200
T1068 Phosphorylation PhosphoSitePlus
S1083 Phosphorylation IEDB 32387766
K1084 Ubiquitination PhosphoSitePlus
K1110 Sumoylation PhosphoSitePlus
T1115 Phosphorylation PhosphoSitePlus
S1122 Phosphorylation HPRD   PhosphoSitePlus 18077418
T1131 Phosphorylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation PhosphoSitePlus
T1165 Phosphorylation PhosphoSitePlus
S1168 Phosphorylation PhosphoSitePlus
S1172 Phosphorylation PhosphoSitePlus
T1219 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1222 Ubiquitination PhosphoSitePlus
S1259 Phosphorylation HPRD 20068231
K1276 Ubiquitination PhosphoSitePlus
K1285 Ubiquitination PhosphoSitePlus
K1304 Ubiquitination PhosphoSitePlus
K1308 Acetylation PhosphoSitePlus
K1309 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K41 N41 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K57 N57 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S118 L118 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S124 P124 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S134 L134 Biomuta DOID:4159 / skin cancer [ cosmic ]
S366 C366 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
S367 * Biomuta DOID:263 / kidney cancer [ cosmic ]
S403 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S451 Y451 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S465 F465 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S468 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S471 T471 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S481 F481 Biomuta DOID:1324 / lung cancer [ cosmic ]
T534 K534 Biomuta DOID:1324 / lung cancer [ cosmic ]
S868 L868 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S880 L880 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T898 M898 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S903 Y903 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1011 A1011 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1068 M1068 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T1115 I1115 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1135 F1135 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1165 S1165 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
K1304 M1304 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]