iPTMnet Report for Q9ULE0 (WWC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9ULE0 / WWC3_HUMAN
Protein Name Protein WWC3
Gene Name Name: WWC3
Synonyms:KIAA1280;
Organism Homo sapiens (Human)

PRO ID PR:Q9ULE0
DAG View
PRO Name protein WWC3 (human)
Definition A protein WWC3 that is encoded in the genome of human.
Short Label hWWC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9ULE0 (WWC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus
Y57 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
S351 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
R369 Methylation PhosphoSitePlus
R376 Methylation PhosphoSitePlus
S378 Phosphorylation HPRD 18669648
S420 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
T445 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S479 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S551 Phosphorylation PhosphoSitePlus
S563 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
Y569 Phosphorylation PhosphoSitePlus
Y643 Phosphorylation PhosphoSitePlus
Y655 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
T736 Phosphorylation PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S883 Phosphorylation PhosphoSitePlus
S890 Phosphorylation PhosphoSitePlus
S907 Phosphorylation PhosphoSitePlus
T909 Phosphorylation PhosphoSitePlus
S911 Phosphorylation PhosphoSitePlus
S925 Phosphorylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
S929 Phosphorylation PhosphoSitePlus
S930 Phosphorylation PhosphoSitePlus
S957 Phosphorylation PhosphoSitePlus
K1044 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S170 R170 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S351 F351 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R369 H369 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R369 C369 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R376 S376 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
R376 C376 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R376 H376 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
T445 M445 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S479 L479 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
S563 Y563 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S563 F563 Biomuta DOID:4159 / skin cancer [ cosmic ]
S567 L567 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S746 F746 Biomuta DOID:4159 / skin cancer [ cosmic ]
S757 Y757 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S863 L863 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S927 C927 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S927 I927 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S927 N927 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S930 L930 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S930 P930 Biomuta DOID:363 / uterine cancer [ icgc ]
K1044 N1044 Biomuta DOID:363 / uterine cancer [ icgc ]