iPTMnet Report for Q9ULB1 (NRXN1)
Protein Information
UniProt AC / UniProt ID | Q9ULB1 / NRX1A_HUMAN |
Protein Name | Neurexin-1 precursor |
Gene Name | Name: NRXN1 Synonyms:KIAA0578; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9ULB1 |
PRO Name | neurexin-1-alpha (human) |
Definition | A neurexin-1-alpha that is encoded in the genome of human. |
Short Label | hNRXN1-alpha |
Category | organism-seqgroup |
Q9ULB1 (NRXN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N125 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
T324 | Phosphorylation | score1 | PhosphoSitePlus | |||
S341 | Phosphorylation | score1 | PhosphoSitePlus | |||
S664 | Phosphorylation | score1 | PhosphoSitePlus | |||
T665 | Phosphorylation | score1 | PhosphoSitePlus | |||
S671 | Phosphorylation | score1 | PhosphoSitePlus | |||
S673 | Phosphorylation | score1 | PhosphoSitePlus | |||
R747 | Methylation | score1 | PhosphoSitePlus | |||
T758 | Phosphorylation | score1 | PhosphoSitePlus | |||
S760 | Phosphorylation | score1 | PhosphoSitePlus | |||
T811 | Phosphorylation | score1 | IEDB | 35494241 | ||
T1002 | Phosphorylation | score1 | IEDB | 35494241 | ||
S1024 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
Y1027 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1136 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1340 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1420 | Phosphorylation | score1 | IEDB | 35494241 | ||
Y1441 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1475 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S413 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S341 | Y341 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
T665 | A665 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S673 | P673 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R747 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] | |
R747 | Q747 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T811 | R811 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T1002 | I1002 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S1024 | T1024 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
Y1420 | H1420 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y1420 | F1420 | Biomuta | DOID:3953 / adrenal gland cancer [ tcga ] |